Evidence map›Paper›PMID 30788764›Full record

ReviewMolecular biology reports2019

Functions of RNA N6-methyladenosine modification in cancer progression.

Bing Chen, Ya Li, Ruifeng Song, Chen Xue, Feng Xu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. METTL3-mediated mHeliyon · 2024
    Article
  8. The role of regulators of RNA mGenes & diseases · 2023
    Review
  9. Article
  10. Article
  11. Effect of Pharmacological Inhibition of Fat-Mass and Obesity-Associated Protein on Nerve Trauma-Induced Pain Hypersensitivities.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Gene Characteristics and Prognostic Values of mJournal of healthcare engineering · 2021
    Article
  16. Article
  17. NAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2020
    Article
  18. Gene Signatures and Prognostic Values of mFrontiers in oncology · 2020
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bing Chen *Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Eastern Road, Zhengzhou, 450052, People's Republic of China.
Ya Li *Department of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Eastern Road, Zhengzhou, 450052, People's Republic of China.
Ruifeng SongDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Eastern Road, Zhengzhou, 450052, People's Republic of China.
Chen XueDepartment of Infectious Diseases, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Eastern Road, Zhengzhou, 450052, People's Republic of China.
Feng XuDepartment of Gastroenterology, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Eastern Road, Zhengzhou, 450052, People's Republic of China. fccxuf@zzu.edu.cn.

Funding

the Key Project of scientific research Foundation for Colleges and Universities in Henan Province 16A320081the National Natural Science Foundation of China 81802325
6 · The paper itself

Abstract

N6-methyladenosine (m6A) serves as a major RNA methylation modification and impacts the initiation and progression of various human cancers through diverse mechanisms. It has been reported that m6A RNA methylation is involved in different physiological and pathological processes, including stem cell differentiation and motility, immune response, cellular stress, tissue renewal and viral infection. In this review, the m6A modification and its regulatory functions in a few major cancers is introduced. The detection approaches for the m6A sites identification are discussed. Additionally, the potential of the RNA m6A modification in clinical application is discussed.

Indexed as

Disease ProgressionAdenosineAnimalsHumansMethylationNeoplasmsRNAAdenosineN-methyladenosineRNACancer progressionClinical applicationDetection approachesPhysiological and pathological processesRNA N6-methyladenosine modification

Identifiers

PMID30788764

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.