ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019
Impact of regadenoson-induced myocardial creep on dynamic Rubidium-82 PET myocardial blood flow quantification.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 39 citations in OpenAlex.
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- Patient-centric performance and interpretation of positron emission tomography /computed tomography myocardial perfusion imaging: a clinical consensus statement of the European Association of Cardiovascular Imaging of the European Society of Cardiology.European heart journal. Imaging methods and practice · 2026Review
- Protocol optimization and myocardial blood flow quantification in dynamic myocardial perfusion CT-where do we stand?European radiology · 2025Article
- Inter-Software Reproducibility of Quantitative Values of Myocardial Blood Flow and Coronary Flow Reserve Acquired by [Diagnostics (Basel, Switzerland) · 2025Article
- Downward myocardial creep during stress PET imaging is inversely associated with mortality.European journal of nuclear medicine and molecular imaging · 2024Article
- Detection and correction of patient motion in dynamicJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Myocardial creep and cardiorespiratory motion correction improves diagnostic accuracy of Rubidium-82 cardiac positron emission tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Patient-tailored risk assessment of obstructive coronary artery disease using Rubidium-82 PET-based myocardial flow quantification with visual interpretation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Motion correction for diagnosis of cardiac sarcoidosis-do we have all the answers?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Measuring myocardial blood flow using dynamic myocardial perfusion SPECT: artifacts and pitfalls.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- Machine learning based model to diagnose obstructive coronary artery disease using calcium scoring, PET imaging, and clinical data.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Effect of temporal sampling protocols on myocardial blood flow measurements using Rubidium-82 PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Influence of patient motion on quantitative accuracy in cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The next step in improving (semi-)quantitative MPI PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- The long fight against motion artifacts in cardiac PET.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- A preliminary evaluation of a high temporal resolution data-driven motion correction algorithm for rubidium-82 on a SiPM PET-CT system.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Value of SiPM PET in myocardial perfusion imaging using Rubidium-82.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
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6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundRepositioning of the heart during myocardial perfusion imaging (MPI) using Rubidium-82 (Rb-82) PET may occur when using regadenoson. Our aim was to determine the prevalence and the effect of correcting for this myocardial creep on myocardial blood flow (MBF) quantification.
methodsWe retrospectively included 119 consecutive patients who underwent dynamic rest- and regadenoson-induced stress MPI using Rb-82 PET. The presence of myocardial creep was visually assessed in the dynamic stress PET series by identifying differences between the automatically drawn myocardium contour and the activity. Uncorrected and corrected stress MBFs were compared for the three vascular territories (LAD, LCX, and RCA) and for the whole myocardium.
resultsMyocardial creep was observed in 52% of the patients during stress. Mean MBF values decreased after correction in the RCA from 4.0 to 2.7 mL/min/g (P < 0.001), in the whole myocardium from 2.7 to 2.6 mL/min/g (P = 0.01), and increased in the LAD from 2.5 to 2.6 mL/min/g (P = 0.03) and remained comparable in the LCX (P = 0.3).
conclusionsMyocardial creep is a frequent phenomenon when performing regadenoson-induced stress Rb-82 PET and has a significant impact on MBF values, especially in the RCA territory. As this may hamper diagnostic accuracy, myocardial creep correction seems necessary for reliable quantification.
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