SynthesisEndocrine2019
Huge variations in definition and reported incidence of postsurgical hypoparathyroidism: a systematic review.
Synthesis in Endocrine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 3 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Quality of life in patients with hypoparathyroidism receiving standard treatment: an updated systematic review.Endocrine · 2024Pooled it
- What are the real rates of temporary hypoparathyroidism following thyroidectomy? It is a matter of definition: a systematic review.Endocrine · 2021Pooled it
- A mapping review of sacrococcygeal pilonidal sinus disease.Techniques in coloproctology · 2021Pooled it
- Increased mortality in chronic hypoparathyroidism: a nationwide cohort study in Sweden.Endocrine connections · 2026Article
- Predicting permanent hypoparathyroidism after thyroidectomy: role of early postoperative parathyroid hormone levels and surgical factors.BMC endocrine disorders · 2026Article
- Early Detection of Transient Hypoparathyroidism After Total Thyroidectomy: A Single-Center Preliminary Study.Medicina (Kaunas, Lithuania) · 2026Article
- Does Parathyroid Autotransplantation Prevent Hypoparathyroidism After Thyroid Surgery?Annals of surgery · 2026Article
- Hypocalcemia After Cervical Procedures in Patients with a History of Nonbariatric Gastrojejunostomy.Annals of surgical oncology · 2026Article
- Progress and future prospects for the surgical treatment of permanent hypoparathyroidism after thyroid surgery: a narrative review.BMC surgery · 2025Review
- Bone in Parathyroid Diseases Revisited: Evidence From Epidemiological, Surgical and New Drug Outcomes.Endocrine reviews · 2025Review
- The BMI impact on thyroidectomy-related morbidity; a case-matched single institutional analysis.BMC surgery · 2025Observational
- Role of indocyanine green fluorescence and inferior thyroid artery ligation in hypocalcemia after total-thyroidectomy.Biomolecules & biomedicine · 2025Article
- Increased risk of vertebral fractures and reduced risk of femur fractures in patients with chronic hypoparathyroidism: a nationwide cohort study in Sweden.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2025Article
- Article
- Development and validation of risk prediction models for permanent hypocalcemia after total thyroidectomy in patients with papillary thyroid carcinoma.Scientific reports · 2025Article
- Calcium and vitamin D substitution for hypoparathyroidism after thyroidectomy - how is it continued after discharge from hospital?Langenbeck's archives of surgery · 2024Article
- Post-thyroidectomy hypoparathyroidism: A clinical surgical dilemma.Saudi medical journal · 2024Review
- Hypoparathyroidism after thyroidectomy: a matter of definition, experience and new adjuncts.Gland surgery · 2024Article
- Article
- Postoperative parathyroid hormone (PTH) is equivalent to perioperative PTH drop in predicting postsurgical hypoparathyroidism.Annals of the Royal College of Surgeons of England · 2024Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe reported incidence of post surgical hypoparathyroidism (HypoPT) varies greatly. Previous research suggests that the definition of HypoPT is not consistent in the literature. We therefore conducted a systematic review to investigate how HypoPT is defined and whether this definition, as well as the selected threshold for hypocalcemia affects the incidence.
methodsUsing a predefined search string we identified all articles in PubMed reporting on the incidence of postsurgical HypoPT from 1st January 2010 to January 2017.
resultsWe identified 89 articles that employed 20 different definition of HypoPT. The incidence of HypoPT varied from 0.0% to 20.2%. The definitions were not associated with incidence of HypoPT. Use of prophylactic post-operative calcium supplements, however decreased the risk of HypoPT (p = 0.03), and there was a trend towards a lower risk of HypoPT when using a definition of hypocalcemia below lower limit of the reference range (p = 0.09).
conclusionThe large number of definitions of HypoPT, as well as the huge variation in incidence point to a problem suggests that the awareness of HypoPT should be raised. Use of prophylactic post-operative calcium supplements may decrease risk of HypoPT. This, however, may be due to reverse causality as awareness of the risk of HypoPT may promote the use of calcium supplementation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.