Evidence map›Paper›PMID 30788520›Full record

ArticleClinical neuroradiology2020

Comparison of Superior and Inferior Division Occlusions Treated with Endovascular Thrombectomy.

Fatih Seker, Johannes Pfaff, Ulf Neuberger, Simon Schieber, Simon Nagel, Peter A Ringleb, Martin Bendszus, Markus A Möhlenbruch

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. A review of acute ischemic stroke caused by distal, medium vessel occlusions.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Review
  2. M2 vessel occlusion characteristics and outcome after endovascular therapy: A post-hoc pooled analysis of MR CLEAN MED, NO-IV and LATE.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  3. Article
  4. M1, M2: Time to Bid Adieu!Stroke (Hoboken, N.J.) · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatih SekerDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Johannes PfaffDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Ulf NeubergerDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Simon SchieberDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Simon NagelDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Peter A RinglebDepartment of Neurology, Heidelberg University Hospital, Heidelberg, Germany.
Martin BendszusDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.
Markus A MöhlenbruchDepartment of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany. markus.moehlenbruch@med.uni-heidelberg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSeveral studies have shown that thrombectomy is safe and effective in occlusions of the M2 segment of the middle cerebral artery. This retrospective study compared superior and inferior division occlusions regarding radiological and clinical outcomes.

methodsBetween 2009 and 2017, patients treated with thrombectomy due to occlusion of the superior or inferior division were selected. Univariate and multivariate analyses were performed to identify predictors of outcome and compare superior and inferior division occlusions.

resultsA total of 140 patients with superior (n = 87) and inferior (n = 53) division occlusion were included. Of patients with inferior division occlusion 66.0% achieved good outcome compared to 48.3% in patients with superior division occlusion (P = 0.041). Time from groin puncture to reperfusion, recanalization success, complication rate, hemorrhage rate and follow-up infarct size were similar in both groups. Independent predictors of good outcome were baseline Alberta Stroke Program Early CT Score (ASPECTS) (odds ratio, OR 1.74, 95% confidence interval, CI 1.21-2.58, P = 0.004), time from groin puncture to reperfusion (OR 0.99, 95% CI 0.98-1.0, P = 0.019) and Thrombolysis In Cerebral Infarction (TICI) score 2b-3 (OR 4.51, 95% CI 1.31-18.74, P = 0.024). Superior division occlusion was an independent predictor of poor outcome (OR 2.41, 95% CI 1.05-5.80, P = 0.042). Dominance of the occluded vessel and side of occlusion were not predictive.

conclusionPatients with superior division occlusion appear to have a lower chance of achieving good outcome despite similar recanalization rates and complication rates compared to inferior division occlusions.

Indexed as

AgedEndovascular ProceduresFemaleHumansInfarction, Middle Cerebral ArteryMaleRetrospective StudiesThrombectomyTreatment OutcomeBranchDistalM2OutcomePeripheralStroke

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.