Evidence map›Paper›PMID 30788458›Full record

ArticleJournal of the American Academy of Orthopaedic Surgeons. Global research & reviews2019

Thumb Amputations Treated With Osseointegrated Percutaneous Prostheses With Up to 25 Years of Follow-up.

Yan Li, Katarzyna Kulbacka-Ortiz, Kerstin Caine-Winterberger, Rickard Brånemark

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. A biosynthetic thumb prosthesis.npj biomedical innovations · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yan LiTrauma and Reparative Medicine Theme, Karolinska University Hospital, Solna, Sweden (Dr. Li); the Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden (Dr. Li); the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Gothenburg, Sweden (Ms. Kulbacka and Ms. Caine-Winterberge); and the Department of Orthopaedics, International Centre for Osseointegration Research, Education and Surgery (iCORES), University of California, San Francisco, CA (Dr. Brånemark); and the Department of Orthopaedics, Gothenburg University, Gothenburg, Sweden (Dr. Brånemark).
Katarzyna Kulbacka-OrtizTrauma and Reparative Medicine Theme, Karolinska University Hospital, Solna, Sweden (Dr. Li); the Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden (Dr. Li); the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Gothenburg, Sweden (Ms. Kulbacka and Ms. Caine-Winterberge); and the Department of Orthopaedics, International Centre for Osseointegration Research, Education and Surgery (iCORES), University of California, San Francisco, CA (Dr. Brånemark); and the Department of Orthopaedics, Gothenburg University, Gothenburg, Sweden (Dr. Brånemark).
Kerstin Caine-WinterbergerTrauma and Reparative Medicine Theme, Karolinska University Hospital, Solna, Sweden (Dr. Li); the Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden (Dr. Li); the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Gothenburg, Sweden (Ms. Kulbacka and Ms. Caine-Winterberge); and the Department of Orthopaedics, International Centre for Osseointegration Research, Education and Surgery (iCORES), University of California, San Francisco, CA (Dr. Brånemark); and the Department of Orthopaedics, Gothenburg University, Gothenburg, Sweden (Dr. Brånemark).
Rickard BrånemarkTrauma and Reparative Medicine Theme, Karolinska University Hospital, Solna, Sweden (Dr. Li); the Division of Orthopedics and Biotechnology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden (Dr. Li); the Centre for Advanced Reconstruction of Extremities (C.A.R.E.), Sahlgrenska University Hospital, Gothenburg, Sweden (Ms. Kulbacka and Ms. Caine-Winterberge); and the Department of Orthopaedics, International Centre for Osseointegration Research, Education and Surgery (iCORES), University of California, San Francisco, CA (Dr. Brånemark); and the Department of Orthopaedics, Gothenburg University, Gothenburg, Sweden (Dr. Brånemark).
Karolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionImplantation of an osseointegrated percutaneous prosthesis provides a reconstruction alternative for thumb amputation without sacrificing donor tissues.

methodsThirteen thumb amputees received osseointegrated prostheses (1990 to 2014). The treatments were started with custom-designed implants. Since 2005, standardized implant components and structured rehabilitation protocols were introduced. The median follow-up period was 9.5 years.

resultsSix patients were lost to follow-up. Seven patients (including all six after the introduction of the standardized protocol) had good osseoperception, grip strength (Jamar) was 28.3 kg on the operated side versus 40.4 kg in the unaffected hand (70%), and key grip strength was 6 versus 9.1 kg. Hand function was 94% of the normal hand. The most common complications were mechanical failures necessitating changes of components (eight times in three patients) and superficial infections (seven times in five patients). Five patients had no complications. The refined implant design and new standardized treatment protocol achieved a 100% cumulative success rate with 9.5 years of follow-up so far. DISCUSSION: Treatment of thumb amputees using bone-anchored percutaneous prostheses seems to be a safe, durable method with excellent short- and medium-long follow-up results. Severe adverse events are few except for implant loosening which occurred only in the early custom-designed group.

Identifiers

PMID30788458
PMCPMC6365303
OpenAlexW2987378948

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.