Evidence map›Paper›PMID 30788283›Full record

ReviewIntegrated pharmacy research & practice2019

Cardiovascular disease as a leading cause of death: how are pharmacists getting involved?

Kevin Mc Namara, Hamzah Alzubaidi, John Keith Jackson

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Integrated pharmacy research & practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 189 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
189citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04444570 unknown statusnot on this mapstarted 2021, after this paper: background citation

Continuous Glycemia Monitoring in Perioperative Period in Patients Undergoing Total Knee or Hip Arthroplasty: a Protocol of Observational Study

TypeobservationalSponsorMedical University of WarsawRan2021 to 2022Enrolled100ConditionsOsteoarthritis, Knee, Osteoarthritis, Hip, Hyperglycemia, Diabetes Mellitus, Type 2ArmsContinuous glycemia measuring device (Dexcom) implantation into the subcutaneous tissue
NCT07692594 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Cardiovascular Health in People With Cystic Fibrosis

Typeobservational_patient_registrySponsorLiverpool Heart and Chest Hospital NHS Foundation TrustRan2026 to 2028Enrolled32ConditionsCystic Fibrosis (CF), Cardiovascular (CV) Risk, Flow-mediated Dilation Evaluation of the Brachial Artery, Pulse Wave Analysis
3 · Its place in the literature

Who cites it

189 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Late IMedicinal research reviews · 2026
    Review
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  19. Omics approaches to understand cardiovascular disease.BMC cardiovascular disorders · 2025
    Article
  20. Epicardial Adipocytes in Cardiac Pathology and Healing.Cardiovascular drugs and therapy · 2025
    Review

129 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kevin Mc NamaraSchool of Medicine, Deakin University, Geelong, VIC, Australia, kevin.mcnamara@deakin.edu.au.
Hamzah AlzubaidiInstitute for Medical Research and College of Pharmacy, University of Sharjah, Sharjah, Sharjah, United Arab Emirates.
John Keith JacksonCentre for Medicine Use & Safety, Faculty of Pharmacy & Pharmaceutical Sciences, Monash University, Melbourne, VIC, Australia, kevin.mcnamara@deakin.edu.au.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are a leading cause of death globally. This article explores the evidence surrounding community pharmacist interventions to reduce cardiovascular events and related mortality and to improve the management of CVD risk factors. We summarize a range of systematic reviews and leading randomized controlled trials and provide critical appraisal. Major observations are that very few trials directly measure clinical outcomes, potentially owing to a range of challenges in this regard. By contrast, there is an extensive, high-quality evidence to suggest that improvements can be achieved for key CVD risk factors such as hypertension, dyslipidemia, tobacco use, and elevated hemoglobin A1c. The heterogeneity of interventions tested and considerable variation of the context under which implementation occurred suggest that caution is warranted in the interpretation of meta-analyses. It is highly important to generate evidence for pharmacist interventions in developing countries where a majority of the global CVD burden will be experienced in the near future. A growing capacity for clinical registry trials and data linkage might allow future research to collect clinical outcomes data more often.

Indexed as

cardiovascular risk factorschronic disease managementdisease screeninghealth servicespreventative health

Identifiers

PMID30788283
PMCPMC6366352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.