Evidence map›Paper›PMID 30788230›Full record

ReviewTranslational lung cancer research2019

Empiric Radiotherapy for Lung Cancer Collaborative Group multi-institutional evidence-based guidelines for the use of empiric stereotactic body radiation therapy for non-small cell lung cancer without pathologic confirmation.

Abigail T Berman, Salma K Jabbour, Anil Vachani, Cliff Robinson, J Isabelle Choi, Pranshu Mohindra, Ramesh Rengan, Jeffrey Bradley, Charles B Simone

Abstract readReview
In one paragraph

Review in Translational lung cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. CyberKnifeJournal of thoracic disease · 2023
    Article
  8. Article
  9. Article
  10. Multiblock Discriminant Analysis of IntegrativeInternational journal of radiation oncology, biology, physics · 2021
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abigail T BermanDepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA.
Salma K JabbourDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ, USA.
Anil VachaniDivision of Pulmonary, Allergy, and Critical Care, Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Cliff RobinsonDepartment of Radiation Oncology, Washington University, St. Louis, MO, USA.
J Isabelle ChoiDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
Pranshu MohindraDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.
Ramesh RenganDepartment of Radiation Oncology, University of Washington, Seattle, WA, USA.
Jeffrey BradleyDepartment of Radiation Oncology, Washington University, St. Louis, MO, USA.
Charles B SimoneDepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USA.

Funding

Dr. Salma Jabbour’s NCI Research Specialist (Clinician Scientist) Award (R50)R50CA275877 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Salma Jabbour · 2023 to 2026
$785k
NCI NIH HHS R50 CA275877
6 · The paper itself

Abstract

The standard of care for managing early stage non-small cell lung cancer (NSCLC) is definitive surgical resection. Stereotactic body radiation therapy (SBRT) has become the standard treatment for patient who are medically inoperable, and it is increasingly being considered as an option in operable patients. With the growing use of screening thoracic CT scans for patients with a history of heavy smoking, as well as improved imaging capabilities, the discovery of small lung nodes has become a common dilemma. As a result, clinicians are increasingly faced with managing lung nodules in patients in whom diagnostic biopsy is not safe or feasible. Herein, we describe the scope of the problem, tools available for predicting the probability that a lung nodule is a malignancy, staging procedures, benefits of pathology-proven and empiric SBRT, considerations of safety based on location of the lesion of concern, and overall efficacy of SBRT.

Indexed as

empiricpathologic confirmationradiographicStereotactic body radiation therapy (SBRT)tissue diagnosis

Identifiers

PMID30788230
PMCPMC6351405

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.