ReviewWorld journal of orthopedics2019
Osteoarticular manifestations of human brucellosis: A review.
Review in World journal of orthopedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
94 citing papers in PubMed, 2 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Research hotspots and development trends ofFrontiers in microbiology · 2025Pooled it
- Quantifying research hotspots and trends in brucella spondylitis: a bibliometric analysis.Frontiers in surgery · 2024Pooled it
- Ankylosing spondylitis following chronic brucellosis: a causal association or separate pathology? A case-based review.Rheumatology international · 2026Review
- Assessing Knowledge, Attitudes and Practices Regarding Brucellosis Among High-Risk Occupational Groups.Veterinary medicine and science · 2026Article
- Shifting risk profiles in the systemic-to-focal transition of brucellosis: a multicenter analysis of spondyloarthritis development.BMC infectious diseases · 2026Article
- Bilateral Brucellar Sacroiliitis Mimicking Tuberculous or Inflammatory Spondyloarthropathy: A Case Report.Clinical case reports · 2026Article
- RETRACTED: Brucella melitensis infection with osteoarticular involvement: First reported cases in Colombia. https://doi.org/10.7705/biomedica.8614Biomedica : revista del Instituto Nacional de Salud · 2026Article
- Article
- Diagnostic Value of Metagenomic Next-Generation Sequencing for Suspected Native Spinal Brucella Infection: A Multicenter Study.Neurospine · 2026Article
- When it's not RA: unmasking Whipple's disease in seronegative, difficult-to-treat rheumatoid arthritis.Clinical rheumatology · 2026Review
- Biological characteristics, human cell interaction mechanisms, and differential clinical outcomes of infection by Brucella melitensis, Brucella abortus, Brucella suis, and Brucella canis.Archives of microbiology · 2026Review
- Multi-Pathogen Knee Infection, Including Treponema pallidum and Brucella: A Case Report.The American journal of case reports · 2026Article
- Brucella Infection of the Sternoclavicular Joint with Innovative Localized Drug Delivery: A Case Report and Review of the Literature.Orthopedic research and reviews · 2026Article
- Feasibility and clinical efficacy of minimally invasive techniques in the treatment of type Ⅱ/Ⅲ brucellar spondylitis.Frontiers in surgery · 2026Article
- Spinal infections.Frontiers in neuroscience · 2026Review
- Analysis of Risk Factors for Postoperative Complications of Thoracolumbar Brucella Spondylitis.Infection and drug resistance · 2026Article
- Metagenomic Next-Generation Sequencing in Brucellar Spondylitis with Discordant Serologic Findings in a Non-Endemic Region: A Case Report and Literature Review.Infection and drug resistance · 2026Article
- A case report of cervical spine epidural abscess caused by brucellosis.Surgical neurology international · 2026Article
- Clinical epidemiological characteristics and treatment outcomes of Brucella spondylitis in Ningxia, China: a 12‑year single‑center retrospective study.BMC infectious diseases · 2025Article
- Multimodal imaging-based interpretable radiomics for differentiating brucella and tuberculosis spondylitis: a two-center study.BMC infectious diseases · 2025Article
34 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brucellosis is a common global zoonotic disease, which is responsible for a range of clinical manifestations. Fever, sweating and musculoskeletal pains are observed in most patients. The most frequent complication of brucellosis is osteoarticular involvement, with 10% to 85% of patients affected. The sacroiliac (up to 80%) and spinal joints (up to 54%) are the most common affected sites. Spondylitis and spondylodiscitis are the most frequent complications of brucellar spinal involvement. Peripheral arthritis, osteomyelitis, discitis, bursitis and tenosynovitis are other osteoarticular manifestations, but with a lower prevalence. Spinal brucellosis has two forms: focal and diffuse. Epidural abscess is a rare complication of spinal brucellosis but can lead to permanent neurological deficits or even death if not treated promptly. Spondylodiscitis is the most severe form of osteoarticular involvement by brucellosis, and can have single- or multi-focal involvement. Early and appropriate diagnosis and treatment of the disease is important in order to have a successful management of the patients with osteoarticular brucellosis. Brucellosis should be considered as a differential diagnosis for sciatic and back pain, especially in endemic regions. Patients with septic arthritis living in endemic areas also need to be evaluated in terms of brucellosis. Physical examination, laboratory tests and imaging techniques are needed to diagnose the disease. Radiography, computed tomography, magnetic resonance imaging (MRI) and bone scintigraphy are imaging techniques for the diagnosis of osteoarticular brucellosis. MRI is helpful to differentiate between pyogenic spondylitis and brucellar spondylitis. Drug medications (antibiotics) and surgery are the only two options for the treatment and cure of osteoarticular brucellosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.