Evidence map›Paper›PMID 30788185›Full record

ArticleJournal of clinical imaging science2019

Volumetric and Shape Analysis of the Subcortical Regions in Schizophrenia Patients: A Pilot Study.

Abdullah Abu Jamea, Muhammed Alblowi, Jamaan Alghamdi, Fahad D Alosaimi, Fahad Al-Bader, Shahid Bashir

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Article in Journal of clinical imaging science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Abdullah Abu JameaDepartment of Radiology and Medical Imaging, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Muhammed AlblowiDepartment of Psychiatry, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Jamaan AlghamdiDepartment of Diagnostic Radiology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Fahad D AlosaimiDepartment of Psychiatry, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Fahad Al-BaderDepartment of Radiology and Medical Imaging, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Shahid BashirNeuroscience Center, King Fahad Specialist Hospital Dammam, Dammam, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveInvestigation of brain structure in disease has been enhanced by developments in shape analysis methods that can identify subtle regional surface distortions. High-resolution magnetic resonance (MR) imaging was used to compare volumetric and shape analysis in schizophrenia (SCZ) patients and healthy controls (CON).

methodsT1-weighted, 1-mm thick MR images were acquired for 15 patients with SCZ and 15 age-matched healthy controls using subcortical volume and shape analysis, which we believe to be complimentary to volumetric measures.

resultsSCZ patients showed significant shape differences compared to healthy controls in the right hippocampus (

conclusionOur results provide evidence for subcortical neuroanatomical changes in patients with SCZ. Hence, shape analysis may aid in the identification of structural biomarkers for identifying individuals of SCZ.

Indexed as

Brain structurehigh-resolution magnetic resonance imagingschizophreniashape analysis

Identifiers

PMID30788185
PMCPMC6380120

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