ArticleJournal of gastrointestinal oncology2019
Gastric squamous cell carcinoma and gastric adenosquamous carcinoma, clinical features and outcomes of rare clinical entities: a National Cancer Database (NCDB) analysis.
Article in Journal of gastrointestinal oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 48 citations in OpenAlex.
- Successful non-surgical management of locally advanced gastric adenocarcinoma with squamous differentiation and programmed death-ligand 1 combined positive score 75: a case report.Journal of medical case reports · 2026Article
- Clinicopathological significance of deficient DNA mismatch repair and MLH1 promoter methylation in gastric adenosquamous carcinoma.Virchows Archiv : an international journal of pathology · 2025Article
- A case of successful pembrolizumab plus FP neoadjuvant chemotherapy for a tumor preoperatively diagnosed as gastric squamous cell carcinoma.Clinical journal of gastroenterology · 2025Article
- EZH2 loss promotes gastric squamous cell carcinoma.Nature communications · 2025Article
- Primary gastric squamous cell carcinoma in a young adult with immunotherapy complications: a case report.Journal of gastrointestinal oncology · 2025Article
- Survival analysis of gastric malignancy patients: identifying key prognostic factors.Translational cancer research · 2025Article
- Primary Gastric Squamous Cell Carcinoma: Challenges in Treatment Strategy.European journal of case reports in internal medicine · 2025Article
- Rare epithelial gastric cancers: a review of the current treatment knowledge.Therapeutic advances in medical oncology · 2025Review
- Long-term remission of microsatellite instability-high adenosquamous carcinoma in gastric antrum: a case report.Frontiers in oncology · 2025Article
- Survival benefit of perioperative chemoradiotherapy in patients with resectable primary gastric adenosquamous carcinoma: a population-based cohort study.Frontiers in oncology · 2025Article
- Case Report: Long-term response control in a patient with metastatic gastric squamous cell carcinoma treated with nivolumab and chemoradiotherapy.Frontiers in immunology · 2025Article
- Predictive Mortality and Gastric Cancer Risk Using Clinical and Socio-Economic Data: A Nationwide Multicenter Cohort Study.Cancers · 2024Article
- Article
- Analysis of clinicopathological characteristics and prognosis on primary gastric adenosquamous carcinoma.Scientific reports · 2024Article
- A 70-Year-Old Man with a Rare Type of Gastric Cancer.Middle East journal of digestive diseases · 2024Article
- Squamous cell carcinoma of the stomach: focus on a heterogeneous disease at diagnosis. Case report and literature review.Frontiers in oncology · 2024Article
- The rare coexistence of gastric and esophagus squamous cell carcinoma: a case report.The Pan African medical journal · 2024Article
- Unusual or Uncommon Histology of Gastric Cancer.Journal of gastric cancer · 2024Review
- Gastric squamous cell carcinoma: A rare malignancy, literature review and management recommendations (Review).Molecular and clinical oncology · 2023Review
- Understanding gastric adenosquamous cell carcinoma: Insights from immunoprofiling.Journal of the Chinese Medical Association : JCMA · 2023Article
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Authors and funding
7 authors at 1 institution in 1 country.
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Abstract
backgroundGastric squamous cell carcinoma (GSCC) and gastric adenosquamous carcinoma (GASC) comprise less than 2% of gastric cancers. The current knowledge about clinical presentation, treatment modalities and outcomes of GSCC and GASC is limited. The aim of this study is to characterize the clinicopathological features, treatment modalities, and outcomes of GSCC and GASC in comparison to gastric adenocarcinoma (GAC) in National Cancer Database (NCDB).
methodsPatients with GSCC, GASC and GAC between 2004 and 2013 were identified using ICD-O-3 histology and topography codes 8070/3, 8560/3, 8140/3 and C16.0-9. Univariate, and multivariate analysis were performed, and Kaplan-Meier curves was used to compare survival based on histological subtype.
resultsA total of 61,215 patients were identified, 836 (1.4%) GSCC, 327 (0.5%) GASC, 60,052 (98.1%) GAC between 2004 and 2013, in which 77.4% was Caucasian and 68.7% was male, 46.6% of tumors were in gastric cardia and 13.7% in gastric antrum. Neoadjuvant and adjuvant chemotherapy was administered in 11.2%, 14.1%, 8.9%
conclusionsGSCC and GASC have poorer survival outcomes compared to GAC. Less patients with GSCC received surgery and adjuvant chemotherapy, more patients with GSCC received radiation therapy.
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