ArticleClinical & translational immunology2019
A high burden of cytomegalovirus marks poor vascular health in transplant recipients more clearly than in the general population.
Article in Clinical & translational immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 17 citations in OpenAlex.
- Mechanisms of the Indirect Effects of CMV Infection in Solid Organ Transplant Recipients: A Narrative Review.Journal of clinical medicine · 2026Review
- Valaciclovir therapy for secondary suppression of immune response to herpesviruses: An exploratory study.PLoS pathogens · 2025Article
- Relationship between cytomegalovirus antibody levels and cognitive performance is dependent on age and genetic risk.BMC neurology · 2025Article
- Article
- Sequencing of the Viral UL111a Gene Directly from Clinical Specimens Reveals Variants of HCMV-Encoded IL-10 That Are Associated with Altered Immune Responses to HCMV.International journal of molecular sciences · 2022Article
- Role of cytomegalovirus infection after kidney transplantation on the subsequent risk of atherosclerotic and thrombotic events.Atherosclerosis plus · 2022Article
- Challenging the Conventional Interpretation of HCMV Seronegativity.Microorganisms · 2021Article
- Cytomegalovirus may influence vascular endothelial health in Indonesian HIV-infected patients after 5 years on ART.AIDS research and therapy · 2021Article
- Don't Go Breaking My Heart: MCMV as a Model for HCMV-Associated Cardiovascular Diseases.Pathogens (Basel, Switzerland) · 2021Review
- Heart Dysfunction Following Long-Term Murine Cytomegalovirus Infection: Fibrosis, Hypertrophy, and Tachycardia.Viral immunology · 2020Article
- Human Cytomegalovirus Infections Are Associated With Elevated Biomarkers of Vascular Injury.Frontiers in cellular and infection microbiology · 2020Article
- The Detection of CMV in Saliva Can Mark a Systemic Infection with CMV in Renal Transplant Recipients.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMeta-analyses have now confirmed that persistent infections with cytomegalovirus (CMV) can accelerate the onset of diseases of ageing, notably cardiovascular pathologies. We address the circumstances in which the association may be strong enough to warrant intervention to reduce the viral burden.
resultsWe compare markers of the burden of CMV with established indices of vascular pathology in healthy adults (
methodsCarotid intima-media thickness, FMD, eGFR and plasma levels of CMV antibodies (reactive with a lysate, CMV IE-1 or CMV gB), ICAM-1, VCAM-1, P-selectin, sIFNαR2, sTNFR1, sCD14 and CRP were determined.
conclusionLevels of CMV antibody predict declining endothelial health in RTR and not in healthy adults, presumably by reflecting a high burden of CMV. The levels of CMV antibodies were a poor reflection of plasma biomarkers thought to reflect 'inflammaging' or vascular damage.
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