Evidence map›Paper›PMID 30788081›Full record

ArticleComputational and structural biotechnology journal2019

Divaricoside Exerts Antitumor Effects, in Part, by Modulating Mcl-1 in Human Oral Squamous Cell Carcinoma Cells.

Jing-Ru Weng, Li-Yuan Bai, Shih-Jiuan Chiu, Chang-Fang Chiu, Wei-Yu Lin, Jing-Lan Hu, Tzong-Ming Shieh

Open access · goldAbstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jing-Ru WengDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.
Li-Yuan BaiCollege of Medicine, China Medical University, Taichung 40402, Taiwan.
Shih-Jiuan ChiuSchool of Pharmacy, Taipei Medical University, Taipei 11042, Taiwan.
Chang-Fang ChiuCollege of Medicine, China Medical University, Taichung 40402, Taiwan.
Wei-Yu LinDepartment of Pharmacy, Kinmen Hospital, Kinmen 89142, Taiwan.
Jing-Lan HuDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 80424, Taiwan.
Tzong-Ming ShiehDepartment of Dental Hygiene, China Medical University, Taichung 40402, Taiwan.
China Medical University · TWNational Sun Yat-sen University · TWNational Quemoy University · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac glycosides (CGs), prescribed to treat congestive heart failure and arrhythmias, exert potent antitumor activity. In this study, divaricoside (DIV), a CG isolated from

Indexed as

ApoptosisAutophagyCardiac glycosideDivaricosideMcl-1Oral squamous cell carcinoma

Identifiers

PMID30788081
PMCPMC6369261
OpenAlexW2913886484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.