Evidence map›Paper›PMID 30787984›Full record

ArticleAmerican journal of translational research2019

Vascular endothelial Cdc42 deficiency delays skin wound-healing processes by increasing IL-1β and TNF-α expression.

Mengying Xu, Jiawen Lv, Ping Wang, Yanxia Liao, Yiran Li, Wen Zhao, Junchao Zen, Zheyu Dong, Zihao Guo, Xiaoyin Bo and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Correlation of the serum cell division cycle 42 with CD4Frontiers in cardiovascular medicine · 2024
    Article
  4. Article
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  11. Review
  12. Comparative Analysis of Inflammatory Response in Surgical Wound Drainage Fluid in Scoliosis Surgery: A Study of Neuromuscular vs. Idiopathic Patients.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Mengying XuDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University Guangzhou 510515, China.
Jiawen LvDepartment of Respiratory and Critical Care Medicine, Nanjing General Hospital of Nanjing Military Region Nanjing, China.
Ping WangGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Department of Histology and Embryology, School of Basic Medical Sciences, Southern Medical University Guangzhou 510515, China.
Yanxia LiaoDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University Guangzhou 510515, China.
Yiran LiDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University Guangzhou 510515, China.
Wen ZhaoDepartment of Medical Imaging, The Third Affiliated Hospital of Southern Medical University Guangzhou 510515, China.
Junchao ZenDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University Guangzhou 510515, China.
Zheyu DongSouthern Medical University Guangzhou 510515, China.
Zihao GuoSouthern Medical University Guangzhou 510515, China.
Xiaoyin BoSouthern Medical University Guangzhou 510515, China.
Min LiuSouthern Medical University Guangzhou 510515, China.
Lin ZhangGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Department of Histology and Embryology, School of Basic Medical Sciences, Southern Medical University Guangzhou 510515, China.
Guodong HuDepartment of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University Guangzhou 510515, China.
Yinghua ChenGuangdong Provincial Key Laboratory of Construction and Detection in Tissue Engineering, Department of Histology and Embryology, School of Basic Medical Sciences, Southern Medical University Guangzhou 510515, China.
Southern Medical University · CNThird Affiliated Hospital of Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiogenesis is an important step in skin wound repair. Angiogenesis is affected by the functions of many types of cells, especially endothelial cells. Cdc42 plays a vital role in endothelial cell function and vascular development; however, the role of Cdc42 in skin microvascular permeability and skin wound healing is unclear. This study investigated the involvement of Cdc42 in skin wound-healing processes based on its known roles in angiogenesis. Full-thickness skin wounds were created on wild-type and inducible vascular-endothelial-specific

Indexed as

angiogenesisCdc42inflammationreepithelializationskin wound

Identifiers

PMID30787984
PMCPMC6357328
OpenAlexW2981033047

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.