Evidence map›Paper›PMID 30787979›Full record

ArticleAmerican journal of translational research2019

Schizandrin A protects against cerebral ischemia-reperfusion injury by suppressing inflammation and oxidative stress and regulating the AMPK/Nrf2 pathway regulation.

Feng Zhou, Maode Wang, Jing Ju, Yuan Wang, Zhibin Liu, Xiaoping Zhao, Yongmei Yan, Shuguang Yan, Xiaozhong Luo, Yongjun Fang

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
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  3. Anatomy & cell biology · 2024
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  16. Pharmacological properties and mechanisms of Notoginsenoside R1 in ischemia-reperfusion injury.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Feng ZhouDepartment of Neurosurgery, First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061, Shaanxi, China.
Maode WangDepartment of Neurosurgery, First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061, Shaanxi, China.
Jing JuOperation Room, Xianyang IRICO Hospital Xianyang 712000, Shaanxi, China.
Yuan WangCombination of Acupuncture and Medicine Innovation Research Center, Shaanxi University of Chinese Medicine Xianyang 712046, Shaanxi, China.
Zhibin LiuCombination of Acupuncture and Medicine Innovation Research Center, Shaanxi University of Chinese Medicine Xianyang 712046, Shaanxi, China.
Xiaoping ZhaoDepartment of Neurosurgery, The Affiliated Hospital of Shaanxi University of Chinese Medicine Xianyang 712020, Shaanxi, China.
Yongmei YanDepartment of Cerebropathy, The Affiliated Hospital of Shaanxi University of Chinese Medicine Xianyang 712020, Shaanxi, China.
Shuguang YanCollege of Basic Medicine, The Shaanxi University of Chinese Medicine Xianyang 712046, Shaanxi, China.
Xiaozhong LuoDepartment of Administration, Xianyang IRICO Hospital Xianyang 712000, Shaanxi, China.
Yongjun FangDepartment of Neurosurgery, The Affiliated Hospital of Shaanxi University of Chinese Medicine Xianyang 712020, Shaanxi, China.
Shaanxi University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammation and oxidative stress are considered major factors in the pathogenesis of ischemic stroke. Increasing evidence has demonstrated that Schizandrin A (Sch A), a lignin compound isolated from

Indexed as

AMPK/Nrf2 pathwayinflammationoxidative stressSchizandrin A

Identifiers

PMID30787979
PMCPMC6357305
OpenAlexW3020993579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.