Evidence map›Paper›PMID 30787876›Full record

ArticleFrontiers in pharmacology2019

Iron-Chelated Polydopamine Decorated Doxorubicin-Loaded Nanodevices for Reactive Oxygen Species Enhanced Cancer Combination Therapy.

Xu-Jing Li, Wen-Tong Li, Zi-Hao-Ran Li, Li-Ping Zhang, Cheng-Cheng Gai, Wei-Fen Zhang, De-Jun Ding

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Cyclodextrin-Modified CeOInternational journal of nanomedicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xu-Jing LiDepartment of Pathology, Weifang Medical University, Weifang, China.
Wen-Tong LiDepartment of Pathology, Weifang Medical University, Weifang, China.
Zi-Hao-Ran LiDepartment of Pathology, Weifang Medical University, Weifang, China.
Li-Ping ZhangCollege of Pharmacy, Weifang Medical University, Weifang, China.
Cheng-Cheng GaiDepartment of Pathology, Weifang Medical University, Weifang, China.
Wei-Fen ZhangCollaborative Innovation Center for Target Drug Delivery System, Weifang Medical University, Weifang, China.
De-Jun DingCollaborative Innovation Center for Target Drug Delivery System, Weifang Medical University, Weifang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination therapy which enhances efficacy and reduces toxicity, has been increasingly applied as a promising strategy for cancer therapy. Here, a reactive oxygen species (ROS) that enhanced combination chemotherapy nanodevices was fabricated based on the Fe-chelated polydopamine (PDA) nanoparticles (NPs). The structure was characterized by dynamic light scattering-autosizer, transmission electron microscopy, energy dispersive spectroscopy, and Fourier-transform infrared (FT-IR) spectrophotometer. The

Indexed as

breast cancercombination therapydoxorubicinpolydopaminereactive oxygen species

Identifiers

PMID30787876
PMCPMC6372743

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.