Evidence map›Paper›PMID 30787866›Full record

ArticleFrontiers in molecular neuroscience2019

Identification of IQM-266, a Novel DREAM Ligand That Modulates K

Diego A Peraza, Pilar Cercós, Pablo Miaja, Yaiza G Merinero, Laura Lagartera, Paula G Socuéllamos, Carolina Izquierdo García, Sara A Sánchez, Alejandro López-Hurtado, Mercedes Martín-Martínez and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. KCells · 2023
    Review
  4. Modulation of KInternational journal of molecular sciences · 2022
    Article
  5. Pharmacological Approaches for the Modulation of the Potassium Channel KInternational journal of molecular sciences · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Diego A PerazaInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Pilar CercósInstituto de Química Médica (IQM), IQM-CSIC, Madrid, Spain.
Pablo MiajaInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Yaiza G MerineroInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Laura LagarteraInstituto de Química Médica (IQM), IQM-CSIC, Madrid, Spain.
Paula G SocuéllamosInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Carolina Izquierdo GarcíaInstituto de Química Médica (IQM), IQM-CSIC, Madrid, Spain.
Sara A SánchezInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Alejandro López-HurtadoCentro Nacional de Biotecnología (CNB), CNB-CSIC, Madrid, Spain.
Mercedes Martín-MartínezInstituto de Química Médica (IQM), IQM-CSIC, Madrid, Spain.
Luis A Olivos-OréInstituto Universitario de Investigación en Neuroquímica & Departamento de Farmacología y Toxicología, Facultad de Veterinaria, UCM, Madrid, Spain.
José R NaranjoCentro Nacional de Biotecnología (CNB), CNB-CSIC, Madrid, Spain.
Antonio R ArtalejoInstituto Universitario de Investigación en Neuroquímica & Departamento de Farmacología y Toxicología, Facultad de Veterinaria, UCM, Madrid, Spain.
Marta Gutiérrez-RodríguezInstituto de Química Médica (IQM), IQM-CSIC, Madrid, Spain.
Carmen ValenzuelaInstituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, Madrid, Spain.
Instituto de Química Médica · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ESInstituto de Salud Carlos III · ESUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Downstream Regulatory Element Antagonist Modulator (DREAM)/KChIP3/calsenilin is a neuronal calcium sensor (NCS) with multiple functions, including the regulation of A-type outward potassium currents (

Indexed as

AlzheimerA-type currentDREAMDREAM ligandsKChIPKV4.3 channels

Identifiers

PMID30787866
PMCPMC6373780
OpenAlexW2911732979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.