ArticleSaudi journal of medicine & medical sciences
Malocclusion and Craniofacial Characteristics in Saudi Adolescents with Sickle Cell Disease.
Article in Saudi journal of medicine & medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Mandibular Osteomyelitis and Acute Soft Head Syndrome in an Adolescent With Sickle Cell Disease.Journal of medical cases · 2026Article
- Review
- Oral manifestations of sickle cell disease and its effects on dental and periodontal health: A systematic review.Journal of advanced periodontology & implant dentistry · 2025Review
- Orofacial anatomical and occlusal changes in patients with sickle cell disease in Kuwait.The Saudi dental journal · 2023Article
- Dental arch form in a sample of Iraqi adults with sickle cell anemia using 3D scanning technique: A cross-sectional study.Journal of orthodontic science · 2023Article
- Orofacial Manifestation and Dental Management of Sickle Cell Disease: A Scoping Review.Anemia · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundSickle cell disease can result in dentofacial abnormalities. However, in Saudi Arabia, there are limited data with respect to orthodontic manifestations in patients with sickle cell disease.
objectiveTo determine the malocclusion and craniofacial characteristics in sickle cell disease adolescents and compare them with that of controls from the Eastern Province of Saudi Arabia.
methodsThis comparative cross-sectional study included 112 Saudi patients with sickle cell disease, aged 12-18 years, and 124 age-matched Saudi controls from three major hospitals in Al Khobar and Dammam, Saudi Arabia. The Dental Aesthetic Index was used to assess malocclusion and orthodontic treatment needs. Digital lateral cephalometric radiographs were recorded for each patient and control, and its analysis included linear and angular measurements.
resultsThe prevalence of malocclusion was 87.5% in sickle cell disease patients and 54% in controls (
conclusionAdolescents with sickle cell disease had a higher prevalence of malocclusion and greater orthodontic treatment needs than controls. Similarly, they had greater incisal crowding, overjet, openbite and posterior crossbite and demonstrated higher SNA, ANB and lower interincisal angles than controls. The findings of this study suggest that adolescents with sickle cell disease should be provided frequent dental examinations and early orthodontic treatment to improve their oral health, and thus quality of life.
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