Evidence map›Paper›PMID 30787604›Full record

ReviewInternational journal of chronic obstructive pulmonary disease

Early management of COPD: where are we now and where do we go from here? A Delphi consensus project.

Fabiano Di Marco, Piero Balbo, Francesco de Blasio, Vittorio Cardaci, Nunzio Crimi, Giuseppe Girbino, Girolamo Pelaia, Pietro Pirina, Pietro Roversi, Pierachille Santus and 4 more

Open access · goldAbstract readConsensus StatementReview
In one paragraph

Review in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Early diagnosis of COPD: myth or a true perspective.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  5. Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians.Respiration; international review of thoracic diseases · 2020
    Article
  6. Treatment of COPD: the simplicity is a resolved complexity.Multidisciplinary respiratory medicine · 2019
    Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 1 country.

Fabiano Di MarcoDepartment of Health Sciences, University of Milan, Respiratory Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy, fabiano.dimarco@unimi.it.
Piero BalboSC Malattie dell'Apparato Respiratorio, AOU Maggiore della Carità, Novara, Italy.
Francesco de BlasioRespiratory Medicine and Pulmonary Rehabilitation Section, Clinic Center S.p.A. Private Hospital, Department of Medicine and Health Sciences "V Tiberio", University of Molise, Campobasso, Italy.
Vittorio CardaciUnit of Pulmonary Rehabilitation, IRCCS "San Raffaele Pisana", Rome, Italy.
Nunzio CrimiUnità Operativa Complessa di Pneumologia e Allergologia, Policlinico Rodolico Vittorio Emanuele, Università di Catania, Catania, Italy.
Giuseppe GirbinoDipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università degli Studi di Messina, Messina, Italy.
Girolamo PelaiaDepartment of Medical and Surgical Sciences, Unit of Respiratory Diseases, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Pietro PirinaRespiratory Unit, AOU Sassari, Sassari, Italy.
Pietro RoversiAzienda Ospedaliera Universitaria, Policlinico di Modena, Modena, Italy.
Pierachille SantusDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Nicola ScichiloneDipartimento Biomedico di Medicina Interna e Specialistica (DIBIMIS), University of Palermo, Palermo, Italy.
Alessandro VatrellaDepartment of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno, Salerno, Italy.
Patrizio PasqualettiFondazione Fatebenefratelli per la Ricerca e la Formazione Sanitaria e Sociale, Rome, Italy.
Mauro CaroneIstituti Clinici Scientifici Maugeri, IRCCS di Cassano delle Murge, Cassano delle Murge (BA), Italy.
University of Milan · ITAzienda Ospedaliero-Universitaria di Modena · ITAzienda Ospedaliero Universitaria di Sassari · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITFondazione Roma · ITIRCCS Ospedale San Raffaele · ITIstituti Clinici Scientifici Maugeri · ITMagna Graecia University · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Messina · ITUniversity of Molise · ITUniversity of Palermo · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is a lack of consensus on the most appropriate early diagnostic strategy, criteria for early access to treatment and follow-up approach for patients with COPD. MATERIALS AND

methodsA Delphi consensus project investigated the early management of COPD. We formulated two questionnaires for completion by pneumologists in Italy.

resultsA total of 207 specialists completed questionnaire 1 and 184 of them questionnaire 2, between November 2016 and October 2017. Early diagnosis of COPD was considered uncommon for 93.2% of the expert panel. Regardless of the definition of "early diagnosis" - a diagnosis made before the clinical manifestation of the disease for most responders (60.4%) - experts were confident of the positive effects of early disease management, which they consider is effective in modifying the natural history of the disease. Lack of awareness of the disease was considered the first limiting factor to early COPD management for 78% of respondents. The most effective steps to reduce functional decline were considered to be smoking cessation, followed by long-acting β2-agonist (LABA)/long-acting muscarinic antagonist (LAMA), LAMA, LABA, and finally inhaled corticosteroid/LABA (

conclusionEarly management of COPD is uncommon, and although data on the effects of early disease management on long-term outcomes are limited, Italian experts are confident of the clinical efficacy of this approach.

Indexed as

Adrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsAdultBronchodilator AgentsConsensusDelphi TechniqueDrug CombinationsEarly DiagnosisEarly Medical InterventionEvidence-Based MedicineFemaleHumansItalyMaleMiddle AgedMuscarinic AntagonistsAdrenal Cortex HormonesAdrenergic beta-2 Receptor AgonistsBronchodilator AgentsDrug CombinationsMuscarinic Antagonistsbronchodilator therapydyspneaItalyrespiratory symptoms

Identifiers

PMID30787604
PMCPMC6366359
OpenAlexW2915035317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.