ArticleNature2019
The centrosome protein AKNA regulates neurogenesis via microtubule organization.
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In one paragraph
Article in Nature, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 91 citations in OpenAlex.
- Identification and Functional Characterization of Novel and Recurrent NTRK1 Variants in Chinese Families With Congenital Insensitivity to Pain With Anhidrosis: A Combined Clinical, Genetic, and Functional Study.European journal of neurology · 2026Article
- Mechanical impact on neural stem cell lineage decisions in human brain organoids.EMBO reports · 2026Article
- PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate.Nature communications · 2025Article
- CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies.Journal of cell communication and signaling · 2025Review
- Cell state-specific cytoplasmic density controls spindle architecture and scaling.Nature cell biology · 2025Article
- Protecting centrosomes from fracturing enables efficient cell navigation.Science advances · 2025Article
- Early spinal cord development: from neural tube formation to neurogenesis.Nature reviews. Neuroscience · 2025Review
- UFMylation Modulates OFIP Stability and Centrosomal Localization.Journal of clinical laboratory analysis · 2025Article
- Review
- Identification of AKNA Gene and Its Role for Genetic Susceptibility in Epithelial Ovarian Cancer.Current issues in molecular biology · 2025Article
- Lineage specification in glioblastoma is regulated by METTL7B.Cell reports · 2024Article
- Pan-cellular organelles and suborganelles-from common functions to cellular diversity?Genes & development · 2024Review
- Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain.Nature medicine · 2023Article
- Joint epigenome profiling reveals cell-type-specific gene regulatory programmes in human cortical organoids.Nature cell biology · 2023Article
- Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells.eLife · 2023Article
- Spatial Centrosome Proteomic Profiling of Human iPSC-derived Neural Cells.Bio-protocol · 2023Article
- Centrosome Movements Are TUBG1-Dependent.International journal of molecular sciences · 2023Article
- Identification of Immune-Linked Hub Genes and Diagnostic Model Construction in Schizophrenia.Journal of molecular neuroscience : MN · 2023Article
- Upregulation of TUBG1 expression promotes hepatocellular carcinoma development.Medical oncology (Northwood, London, England) · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
30 authors at 14 institutions in 5 countries.
Germán Camargo Ortega *Institute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Sven Falk *Institute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Pia A Johansson *Institute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Elise PeyreGIGA-Stem Cells, Molecular regulation of neurogenesis, University of Liège, Liège, Belgium.
Loïc BroixGIGA-Stem Cells, Molecular regulation of neurogenesis, University of Liège, Liège, Belgium.
Sanjeeb Kumar SahuInstitute of Molecular Biology (IMB), Mainz, Germany.
William HirstIRI for the Life Sciences, Humboldt University, Berlin, Germany.
Thomas SchlichthaerleMax Planck Institute of Biochemistry, Martinsried, Germany.
Camino De Juan RomeroInstituto de Neurociencias, Consejo Superior de Investigaciones Científicas and Universidad Miguel Hernández, Sant Joan d'Alacant, Spain.
Kalina DraganovaInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Stanislav VinopalLaboratory for Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Kaviya ChinnappaInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Anna GavranovicInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Tugay KarakayaInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Thomas SteiningerInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Juliane Merl-PhamResearch Unit Protein Science, Helmholtz Centre Munich, German Research Center for Environmental Health, Munich, Germany.
Regina FeederleInstitute for Diabetes and Obesity, Monoclonal Antibody Core Facility, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Wei ShaoDevelopmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Song-Hai ShiDevelopmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Stefanie M HauckResearch Unit Protein Science, Helmholtz Centre Munich, German Research Center for Environmental Health, Munich, Germany.
Ralf JungmannMax Planck Institute of Biochemistry, Martinsried, Germany.
Frank BradkeLaboratory for Axon Growth and Regeneration, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Victor BorrellInstituto de Neurociencias, Consejo Superior de Investigaciones Científicas and Universidad Miguel Hernández, Sant Joan d'Alacant, Spain.
Arie GeerlofProtein Expression and Purification Facility, Institute of Structural Biology, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany.
Simone ReberIRI for the Life Sciences, Humboldt University, Berlin, Germany.
Vijay K TiwariInstitute of Molecular Biology (IMB), Mainz, Germany.
Wieland B HuttnerMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Michaela Wilsch-BräuningerMax Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Laurent NguyenGIGA-Stem Cells, Molecular regulation of neurogenesis, University of Liège, Liège, Belgium.
Magdalena GötzInstitute of Stem Cell Research, Helmholtz Center Munich, German Research Center for Environmental Health, Munich, Germany. magdalena.goetz@helmholtz-muenchen.de.
Helmholtz Zentrum München · DELudwig-Maximilians-Universität München · DEUniversity of Liège · BEConsejo Superior de Investigaciones Científicas · ESCornell University · USGerman Center for Neurodegenerative Diseases · DEInstitute of Molecular Biology · DEMax Planck Institute of Biochemistry · DEMax Planck Institute of Molecular Cell Biology and Genetics · DEBerliner Hochschule für Technik · DECenter for Integrated Protein Science Munich · DECenter for NanoScience · DEHumboldt-Universität zu Berlin · DEInstituto de Neurociencias · ES
Funding
Molecular Control of Progenitor Cell Polarity and Cortical NeurogenesisR01DA024681 · NIDA · SLOAN-KETTERING INST CAN RESEARCH · PI JOYNER, ALEXANDRA L. · 2008 to 2020
$5.7MCentrosome Regulation and Function Associated with MicrocephalyR01NS085004 · NINDS · SLOAN-KETTERING INST CAN RESEARCH · PI SHI, SONG-HAI · 2014 to 2018
$2.3MNIDA NIH HHS R01 DA024681NINDS NIH HHS R01 NS085004
Abstract
The expansion of brain size is accompanied by a relative enlargement of the subventricular zone during development. Epithelial-like neural stem cells divide in the ventricular zone at the ventricles of the embryonic brain, self-renew and generate basal progenitors
Indexed as
NeurogenesisAnimalsCell MovementCells, CulturedCentrosomeDNA-Binding ProteinsEpithelial CellsEpithelial-Mesenchymal TransitionHumansIntercellular JunctionsInterphaseLateral VentriclesMammary Glands, AnimalMiceMicrotubulesNuclear ProteinsAKNA protein, humanDNA-Binding ProteinsNuclear ProteinsTranscription Factors
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.