Analysis of Mutants Suggests Kamin Blocking in C. elegans is Due to Interference with Memory Recall Rather than Storage.

Daniel M Merritt, Justina G Melkis, Belinda Kwok, Celina Tran, Derek van der Kooy

Open access · goldAbstract read

In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

0.1field-weighted citation impact, top 54% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

Agency rescues competition for credit assignment among predictive cues from adverse learning conditions.Scientific reports · 2021
Article
The Conscious Nematode: Exploring Hallmarks of Minimal Phenomenal Consciousness inInternational journal of psychological research
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel M MerrittInstitute of Medical Science, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. dmerritt@gmail.com.ORCID 0000-0001-6273-6644

Justina G MelkisDepartment of Physiology, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.

Belinda KwokDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 3E1, Canada.

Celina TranDepartment of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 3E1, Canada.

Derek van der KooyInstitute of Medical Science, University of Toronto, Toronto, Ontario, M5S 1A8, Canada.

University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Higher-order conditioning phenomena, including context conditioning and blocking, occur when conditioning to one set of stimuli interacts with conditioning to a second set of stimuli to modulate the strength of the resultant memories. Here we analyze higher-order conditioning in the nematode worm Caenorhabditis elegans, demonstrating for the first time the presence of blocking in this animal, and dissociating it from context conditioning. We present an initial genetic dissection of these phenomena in a model benzaldehyde/NH

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsConditioning, ClassicalLearningMemoryMemory, Long-TermCaenorhabditis elegans Proteins

Identifiers

PMID30787354

DOI10.1038/s41598-019-38939-3

PMCPMC6382802

OpenAlexW2916001096

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.