Evidence map›Paper›PMID 30787319›Full record

ArticleScientific reports2019

Explaining the unique nature of individual gait patterns with deep learning.

Fabian Horst, Sebastian Lapuschkin, Wojciech Samek, Klaus-Robert Müller, Wolfgang I Schöllhorn

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  11. Interpretable prediction of knee joint loading during tennis serves based on GNN-GRU model and layer-wise relevance propagation.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2025
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  14. Evolution of joint power across the lifespan during walking.Journal of neuroengineering and rehabilitation · 2025
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fabian Horst *Department of Training and Movement Science, Institute of Sport Science, Johannes Gutenberg-University Mainz, Mainz, Rhineland-Palatinate, Germany.ORCID http://orcid.org/0000-0002-3299-5896
Sebastian Lapuschkin *Department of Video Coding & Analytics, Fraunhofer Heinrich Hertz Institute, Berlin, Germany.ORCID http://orcid.org/0000-0002-0762-7258
Wojciech SamekDepartment of Video Coding & Analytics, Fraunhofer Heinrich Hertz Institute, Berlin, Germany. wojciech.samek@hhi.fraunhofer.de.ORCID http://orcid.org/0000-0002-6283-3265
Klaus-Robert MüllerDepartment of Electrical Engineering & Computer Science, Technical University Berlin, Berlin, Germany. klaus-robert.mueller@tu-berlin.de.
Wolfgang I SchöllhornDepartment of Training and Movement Science, Institute of Sport Science, Johannes Gutenberg-University Mainz, Mainz, Rhineland-Palatinate, Germany. wolfgang.schoellhorn@uni-mainz.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine learning (ML) techniques such as (deep) artificial neural networks (DNN) are solving very successfully a plethora of tasks and provide new predictive models for complex physical, chemical, biological and social systems. However, in most cases this comes with the disadvantage of acting as a black box, rarely providing information about what made them arrive at a particular prediction. This black box aspect of ML techniques can be problematic especially in medical diagnoses, so far hampering a clinical acceptance. The present paper studies the uniqueness of individual gait patterns in clinical biomechanics using DNNs. By attributing portions of the model predictions back to the input variables (ground reaction forces and full-body joint angles), the Layer-Wise Relevance Propagation (LRP) technique reliably demonstrates which variables at what time windows of the gait cycle are most relevant for the characterisation of gait patterns from a certain individual. By measuring the time-resolved contribution of each input variable to the prediction of ML techniques such as DNNs, our method describes the first general framework that enables to understand and interpret non-linear ML methods in (biomechanical) gait analysis and thereby supplies a powerful tool for analysis, diagnosis and treatment of human gait.

Indexed as

Deep LearningAdultBiomechanical PhenomenaFemaleGaitHealthy VolunteersHumansMaleYoung Adult

Identifiers

PMID30787319
PMCPMC6382912

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.