Evidence map›Paper›PMID 30787104›Full record

ArticleThe Journal of biological chemistry2019

Folding/unfolding kinetics of G-quadruplexes upstream of the P1 promoter of the human

Yuanlei Cheng, Qingnan Tang, Yutong Li, Yashuo Zhang, Chuyuan Zhao, Jie Yan, Huijuan You

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 52 citations in OpenAlex.

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  15. G-quadruplex DNA: a novel target for drug design.Cellular and molecular life sciences : CMLS · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yuanlei ChengFrom the School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, China.
Qingnan Tangthe Department of Physics, National University of Singapore, Singapore 117542, Singapore.
Yutong LiFrom the School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, China.
Yashuo ZhangFrom the School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, China.
Chuyuan Zhaothe Department of Physics, National University of Singapore, Singapore 117542, Singapore.
Jie Yanthe Department of Physics, National University of Singapore, Singapore 117542, Singapore; the Mechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.
Huijuan YouFrom the School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, China. Electronic address: youhuijuan@hust.edu.cn.
Huazhong University of Science and Technology · CNNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The G-rich Pu39 region of the P1 promoter of the oncogene

Indexed as

G-QuadruplexesPromoter Regions, GeneticProto-Oncogene ProteinsTranscription FactorsB-Cell Lymphoma 3 ProteinDNAGene Expression RegulationHumansKineticsB-Cell Lymphoma 3 ProteinBCL3 protein, humanDNAProto-Oncogene ProteinsTranscription FactorsB-cell lymphoma 2 (Bcl-2)DNA secondary structurefolding/unfolding kineticsforce spectroscopyG-quadruplexmagnetic tweezersoncogene promoterpromotersingle-molecule biophysicstranscription regulation

Identifiers

PMID30787104
PMCPMC6463710
OpenAlexW2918019000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.