Evidence map›Paper›PMID 30787095›Full record

ArticleBMJ open2019

Trends in self-poisoning and psychotropic drug use in people aged 5-19 years: a population-based retrospective cohort study in Australia.

Rose Cairns, Emily A Karanges, Anselm Wong, Jared A Brown, Jeff Robinson, Sallie-Anne Pearson, Andrew H Dawson, Nicholas A Buckley

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Adapting a codesign process with young people to prioritize outcomes for a systematic review of interventions to prevent self-harm and suicide.Health expectations : an international journal of public participation in health care and health policy · 2022
    Pooled it
  3. Interventions for self-harm in children and adolescents.The Cochrane database of systematic reviews · 2021
    Pooled it
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  10. Intended and suicidal trauma to the anterior neck in Finnish young adults.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Rose CairnsNSW Poisons Information Centre, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.ORCID 0000-0002-8946-5079
Emily A KarangesCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.
Anselm WongVictorian Poisons Information Centre and Austin Toxicology Service, Austin Health, Heidelberg, Victoria, Australia.
Jared A BrownNSW Poisons Information Centre, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Jeff RobinsonVictorian Poisons Information Centre, Austin Health, Heidelberg, Victoria, Australia.
Sallie-Anne PearsonCentre for Big Data Research in Health, University of New South Wales, Sydney, New South Wales, Australia.
Andrew H DawsonNSW Poisons Information Centre, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
Nicholas A BuckleyNSW Poisons Information Centre, The Children's Hospital at Westmead, Sydney, New South Wales, Australia.
The University of Sydney · AUAustin Health · AUUNSW Sydney · AUChildren's Hospital at Westmead · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo characterise trends in self-poisoning and psychotropic medicine use in young Australians.

designPopulation-based retrospective cohort study.

settingCalls taken by the New South Wales and Victorian Poisons Information Centres (2006-2016, accounting for 70% of Australian poisoning calls); medicine dispensings in the 10% sample of Australian Pharmaceutical Benefits Scheme data (July 2012 to June 2016).

participantsPeople aged 5-19 years.

main outcome measuresYearly trends in intentional poisoning exposure calls, substances taken in intentional poisonings, a prevalence of psychotropic use (dispensing of antidepressants, antipsychotics, benzodiazepines and medicines for attention deficit hyperactivity disorder (ADHD)).

resultsThere were 33 501 intentional poisonings in people aged 5-19 years, with an increase of 8.39% per year (95% CI 6.08% to 10.74%, p<0.0001), with a 98% increase overall, 2006-2016. This effect was driven by increased poisonings in those born after 1997, suggesting a birth cohort effect. Females outnumbered males 3:1. Substances most commonly taken in self-poisonings were paracetamol, ibuprofen, fluoxetine, ethanol, quetiapine, paracetamol/opioid combinations, sertraline and escitalopram. Psychotropic dispensing also increased, with selective serotonin reuptake inhibitors (SSRIs) increasing 40% and 35% July 2012 to June 2016 in those aged 5-14 and 15-19, respectively. Fluoxetine was the most dispensed SSRI. Antipsychotics increased by 13% and 10%, while ADHD medication dispensing increased by 16% and 10%, in those aged 5-14 and 15-19, respectively. Conversely, dispensing of benzodiazepines to these age groups decreased by 4% and 5%, respectively.

conclusionsOur results signal a generation that is increasingly engaging in self-harm and is increasingly prescribed psychotropic medications. These findings indicate growing mental distress in this cohort. Since people who self-harm are at increased risk of suicide later in life, these results may foretell future increases in suicide rates in Australia.

Indexed as

AdolescentAge DistributionAttention Deficit Disorder with HyperactivityAustraliaBenzodiazepinesChildChild, PreschoolDrug PrescriptionsFemaleHumansMalePoisoningPsychotropic DrugsRegression AnalysisRetrospective StudiesSelf-Injurious BehaviorBenzodiazepinesPsychotropic Drugsclinical pharmacologypublic healthtoxicology

Identifiers

PMID30787095
PMCPMC6398641
OpenAlexW2917799434

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.