ArticleBMJ open2019
Adiposity measures and their validity in estimating risk of hypertension in South Asian children: a cross-sectional study.
Article in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of anthropometric indices for discriminating elevated blood pressure in pediatric population: a systematic review and a meta-analysis.BMC pediatrics · 2022Pooled it
- Adiposity and Blood Pressure in Children and Adolescents: A National Cross-Sectional Study in China.Healthcare (Basel, Switzerland) · 2026Article
- Sex differences in blood pressure and physical activity among socioeconomically vulnerable Portuguese schoolchildren aged 6 to 10 years: insights from the BeE-school Project.BMC pediatrics · 2026Article
- Indices of insulin resistance and adiposity can detect obesity-related morbidity in pediatrics.Saudi medical journal · 2022Article
- Deriving Normative Data on 24-Hour Ambulatory Blood Pressure Monitoring for South Asian Children (ASHA): A Clinical Research Protocol.Canadian journal of kidney health and disease · 2022Article
- Waist-to-height-ratio is associated with sustained hypertension in children and adolescents with high office blood pressure.Frontiers in cardiovascular medicine · 2022Article
- Exploring Knowledge and Perspectives of South Asian Children and Their Parents Regarding Healthy Cardiovascular Behaviors: A Qualitative Analysis.Global pediatric health · 2020Article
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Authors and funding
9 authors.
Funding
Abstract
objectiveGiven the South Asian phenotype of higher body fat at similar body mass index (BMI) relative to Caucasians, we sought to explore the association between prominent adiposity indicators with blood pressure (BP) and hypertension, to compare the accuracy of these indicators in estimating hypertension, and to provide cut-off values associated with adverse hypertension risk in South Asian children.
designCross-sectional study.
settingCommunity-based recruitment in two Canadian cities (Hamilton and Surrey).
participantsSouth Asian children (n=762) were recruited from two Canadian cities. Waist circumference, waist to height ratio and BMI were determined. Body fat percentage was assessed by bioelectrical impedance analysis and BP was assessed using an automated device. All variables (except body fat percentage) were transformed to z-scores using published standards. OUTCOME MEASURES: Linear and Poisson regression was used to explore associations between the adiposity indicators with BP z-score and hypertension. Receiver operating curve (ROC) analysis was used to explore the strength of the adiposity indicators in estimating hypertension risk and sex-stratified optimal adiposity cut-off values associated with hypertension risk.
resultsSignificant associations were detected in adjusted and unadjusted models between the adiposity indicators with BP z-score and hypertension (p<0.01 for all). The area under the curve (AUC) values for the adiposity indicators for boys and girls ranged from 0.74 to 0.80, suggesting that the adiposity indicators are fair measures of estimating hypertension risk. Sex-stratified cut-off associated with adverse risk of hypertension for girls and boys, respectively, were at the 92nd and 82nd percentile for BMI z-scores, 65th and 80th percentile for WC z-score, 63rd and 67th percentile for WHtR z-score and at 29.8% and 23.5% for body fat.
conclusionOur results show associations between adiposity indicators with BP and hypertension and suggests that South Asian children might be at adverse risk of hypertension at levels of adiposity considered normal.
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