Evidence map›Paper›PMID 30787026›Full record

ArticleBMJ case reports2019

Acute adrenal failure: a potentially fatal consequence of an adulterated herbal remedy.

Harminder Sensi, Harit Buch, Loretta Ford, Rousseau Gama

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Harminder SensiChemical Pathology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK.
Harit BuchEndocrinology and Diabetes, New Cross Hospital, Wolverhampton, UK.
Loretta FordChemical Pathology, New Cross Hospital, Wolverhampton, UK.
Rousseau GamaChemical Pathology, New Cross Hospital, Wolverhampton, UK.
New Cross Hospital · GBWolverhampton Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herbal remedies adulterated with glucocorticoids can cause Cushing's syndrome. We report a severe presentation of a 'herbal remedy' adulterated with glucocorticoids; causing a potentially fatal adrenal crisis precipitated by acute illness. Investigations were consistent with adrenal suppression and confirmed, after tablet analysis, to be due to a 'herbal remedy' containing synthetic betamethasone/dexamethasone. This case highlights the need for clinical vigilance and patient education about the potential risks associated with the use of unlicensed treatments and the role of tablet analysis in routine biochemistry.

Indexed as

Acute DiseaseAdrenal InsufficiencyAftercareAnti-Inflammatory AgentsDrug ContaminationFemaleHumansHydrocortisoneIntensive Care UnitsMiddle AgedPakistanPhytotherapyTreatment OutcomeAnti-Inflammatory AgentsHydrocortisoneadrenal disordersendocrine system

Identifiers

PMID30787026
PMCPMC6388792
OpenAlexW2917650488

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.