Evidence map›Paper›PMID 30787019›Full record

ArticleBlood advances2019

Cells of adult T-cell leukemia evade HTLV-1 Tax/NF-κB hyperactivation-induced senescence.

Abigail M Druck Shudofsky, Chou-Zen Giam

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Clinical and Mechanistic Implications of R-Loops in Human Leukemias.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
  7. Article
  8. NF-κB-induced R-loop accumulation and DNA damage select for nucleotide excision repair deficiencies in adult T cell leukemia.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Abigail M Druck ShudofskyDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD.
Chou-Zen GiamDepartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD.ORCID 0000-0001-9656-5097
Uniformed Services University of the Health Sciences · US

Funding

Cell Cycle Regulation and Adult T Cell LeukemiaR01CA140963 · NCI · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI GIAM, CHOU-ZEN · 2010 to 2014
$1.8M
Clonal Expansion of HTLV-1-Infected Cells and Adult T Cell LeukemiaR21CA216660 · NCI · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI GIAM, CHOU-ZEN · 2018 to 2019
$364k
NCI NIH HHS R01 CA140963NCI NIH HHS R21 CA216660
6 · The paper itself

Abstract

Human T-cell leukemia virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia/lymphoma (ATL). The HTLV-1 viral

Indexed as

Genes, pXAdultCell CycleCell Line, TumorCellular SenescenceHTLV-I InfectionsHumansHuman T-lymphotropic virus 1Leukemia-Lymphoma, Adult T-CellNF-kappa BNF-kappa B

Identifiers

PMID30787019
PMCPMC6391679
OpenAlexW2916892019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.