ArticleBMC ophthalmology2019
Decreased retinal nerve fiber layer thickness in patients with cerebral venous thrombosis.
Article in BMC ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Artificial intelligence in stroke risk assessment and management via retinal imaging.Frontiers in computational neuroscience · 2025Review
- Neuroimaging markers of intracranial hypertension in cerebral venous thrombosis: A systematic review and meta-analysis.Surgical neurology international · 2025Review
- Clinical value of neuroimaging indicators of intracranial hypertension in patients with cerebral venous thrombosis.Neuroradiology · 2024Article
- Optic nerve sheath diameter and its implications in the evaluation of cerebral venous sinus thrombosis.Polish journal of radiology · 2022Article
- Cerebral Venous Thrombosis: an Update.Current neurology and neuroscience reports · 2019Review
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
backgroundTo identify thickness variations in the retinal nerve fiber layer around the optic disc and macula in patients with cerebral vein thrombosis (CVT) without papilledema.
methodsThis study included 28 patients with CVT diagnosis and appropriate treatment. Detailed ophthalmologic examination found bilateral vision 10/10, vision field test normal and fundus examination found no papilledema images. The patients had macular and optic retinal nerve fiber layer thickness (RNFL) measured with spectral domain-optical coherence tomography (SD-OCT) (Optovue, Fremont, CA). Patients had retinal nerve fiber thickness compared with a control group.
resultsWhen the effect on the macula and RNFL near the optic nerve disk is investigated, there was significant thinning identified in the macula inferior inner, temporal inner, superior inner and temporal outer quadrants (p = 0.009, 0.001, 0.026, 0.014, respectively) and in the inferior temporal quadrant of the optic nerve disk (p = 0.020) in CVT patients compared to normal individuals.
conclusionsEven after appropriate treatment of CVT patients, axonal loss was identified with OCT. As a result, it may be important to use OCT measurements to monitor CVT treatment.
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