ArticleRespirology (Carlton, Vic.)2019
Quantitative CT-derived vessel metrics in idiopathic pulmonary fibrosis: A structure-function study.
Article in Respirology (Carlton, Vic.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 29 citations in OpenAlex.
- e-Lung computed tomography biomarkers are associated with outcomes in fibrotic interstitial lung diseases.ERJ open research · 2026Article
- Pulmonary Artery and Vein Morphology as an Imaging Biomarker for the Diagnosis of Pulmonary Hypertension.Diagnostics (Basel, Switzerland) · 2026Article
- Absolute and lung volume-normalized deep learning-derived pulmonary vascular measures in idiopathic pulmonary fibrosis: distinct clinical associations and the role of lung volume in prognosis.Frontiers in medicine · 2026Article
- Assessing pulmonary vascular remodeling in connective tissue disease-associated interstitial lung disease: a CT-based quantitative analysis.Quantitative imaging in medicine and surgery · 2025Article
- Ectopic Expansion of Pulmonary Vasculature in Fibrotic Lung Disease and Lung Adenocarcinoma Marked by Proangiogenic COL15A1+ Endothelial Cells.Pulmonary circulation · 2025Article
- Age-related lung structure changes by quantitative assessment: a cross-sectional study in a Chinese male cohort.Frontiers in aging · 2025Article
- Vascular volume changes in radiological patterns of usual interstitial pneumonia in patients with type 2 diabetes.Diabetology & metabolic syndrome · 2024Article
- Vascular involvement in idiopathic pulmonary fibrosis.ERJ open research · 2024Review
- A New Retest-Stable Tortuosity Metric for Retinal Vessel Analyses.Investigative ophthalmology & visual science · 2024Article
- Deep Learning-based Segmentation of Computed Tomography Scans Predicts Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2024Article
- Pulmonary Hypertension in Idiopathic Interstitial Pneumonia Is Associated with Small Vessel Pruning.American journal of respiratory and critical care medicine · 2024Article
- Quantitative chest computed tomography predicts mortality in systemic sclerosis: A longitudinal study.PloS one · 2024Article
- Expiratory Venous Volume and Arterial Tortuosity are Associated with Disease Severity and Mortality Risk in Patients with COPD: Results from COSYCONET.International journal of chronic obstructive pulmonary disease · 2024Observational
- Idiopathic pulmonary fibrosis disease progression: a dynamic quantitative chest computed tomography follow-up analysis.Quantitative imaging in medicine and surgery · 2023Article
- Quantitative analysis of high-resolution computed tomography features of idiopathic pulmonary fibrosis: a structure-function correlation study.Quantitative imaging in medicine and surgery · 2022Article
- Pulmonary vascular volume is associated with DLCO and fibrotic score in idiopathic pulmonary fibrosis: an observational study.BMC medical imaging · 2022Observational
- Correlation of respiratory oscillometry with CT image analysis in a prospective cohort of idiopathic pulmonary fibrosis.BMJ open respiratory research · 2022Article
- Severe pulmonary hypertension associated with lung disease is characterised by a loss of small pulmonary vessels on quantitative computed tomography.ERJ open research · 2022Article
- Contributions of Emphysema and Functional Small Airway Disease on Intrapulmonary Vascular Volume in COPD.International journal of chronic obstructive pulmonary disease · 2022Article
- Vascular Pruning on CT and Interstitial Lung Abnormalities in the Framingham Heart Study.Chest · 2021Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
BACKGROUND AND
objectiveThis study aimed to investigate whether quantitative lung vessel morphology determined by a new fully automated algorithm is associated with functional indices in idiopathic pulmonary fibrosis (IPF).
methodsA total of 152 IPF patients had vessel volume, density, tortuosity and heterogeneity quantified from computed tomography (CT) images by a fully automated algorithm. Separate quantitation of vessel metrics in pulmonary arteries and veins was performed in 106 patients. Results were evaluated against readouts from lung function tests.
resultsNormalized vessel volume expressed as a percentage of total lung volume was moderately correlated with functional indices on univariable linear regression analysis: forced vital capacity (R
conclusionOur study confirms previous observations of links between vessel volume and functional measures of disease severity in IPF using a new vessel quantitation tool. Additionally, the new tool shows independent linkages of normalized vessel volume and vessel heterogeneity with functional indices. Quantitative vessel metrics do not appear to reflect vasculopathic damage in IPF.
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