ArticleInternational braz j urol : official journal of the Brazilian Society of Urology
Hematologic parameters and neutrophil / lymphocyte ratio in the prediction of urethroplasty success.
Article in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 12 citations in OpenAlex.
- Posterior urethroplasty for pelvic fracture urethral injuries: risk factors for recurrence and complications.World journal of urology · 2025Article
- Investigation of risk factors in the development of recurrent urethral stricture after internal urethrotomy.World journal of clinical cases · 2024Article
- Inflammation indexes and machine-learning algorithm in predicting urethroplasty success.Investigative and clinical urology · 2024Article
- Effect of Haematological Parameters in the Development of Urethrocutaneous Fistula After Hypospadias Surgery.Cureus · 2023Article
- The contribution of the immune system to genitourinary fibrosis.Experimental biology and medicine (Maywood, N.J.) · 2022Article
- Editorial Comment: Larger patients shouldn't have fewer options: urethroplasty is safe in the obese.International braz j urol : official journal of the Brazilian Society of UrologyArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe pathophysiology of urethral stricture and its recurrence remains vague and one of the important causes is progressive infl ammation. It has been shown in recent years that the neutrophil / lymphocyte ratio is a marker of systemic infl ammation and is associated with prognosis in many cardiovascular diseases, malignancies and chronic infl ammatory diseases. We assessed simple systemic infl ammation markers preoperatively and surgical techniques for urethral stricture recurrence after urethroplasty. PATIENTS AND
methodsAfter exclusion criteria applied, a total of 117 male cases operated with urethroplasty in our clinic between January 2012 and June 2017 were included in the study and analyzed retrospectively. Localization and length of the strictures of the patients, neutrophil counts and percentages, lymphocyte counts and percentages, and neutrophil / lymphocyte ratios in preoperative peripheral blood samples were statistically analyzed. Recurrent stricture during fi rst 12 months follow-up after the surgery has been assessed as recurrence.
resultsThe mean age of the patients was 54.12 ± 16.35 and the mean urethral stricture length was 3.44 ± 1.83 cm. Recurrence was observed in 30.1% of cases who received buccal graft, 30% in penile skin applied cases and 26.1% of cases treated with end-to-end anastomosis and there was no statistically signifi cant difference between neutrophil, lymphocyte, neutrophil / lymphocyte ratio and average stricture segment length between recurrent and non-recurrent cases (p > 0.005).
conclusionsWe consider that neutrophil, lymphocyte counts and their ratio prior to urethroplasty and the technique performed are not parameters that can be used to predict stricture recurrence. Prospective and randomized new trials with larger patient populations are needed to make more accurate judgments about the role of these inflammatory parameters.
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