Evidence map›Paper›PMID 30785084›Full record

ArticleRedox biology2019

TUDCA-treated chronic kidney disease-derived hMSCs improve therapeutic efficacy in ischemic disease via PrP

Yeo Min Yoon, SangMin Kim, Yong-Seok Han, Chul Won Yun, Jun Hee Lee, Hyunjin Noh, Sang Hun Lee

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Knockdown of CK2α reducesInternational journal of medical sciences · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yeo Min YoonMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.
SangMin KimMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.
Yong-Seok HanMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.
Chul Won YunMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea.
Jun Hee LeeDepartment of Pharmacology and Toxicology, University of Alabama at Birmingham School of Medicine, Birmingham, AL, 35294, USA.
Hyunjin NohDepartment of Internal Medicine, Soonchunhyang University, Seoul, Republic of Korea; Hyonam Kidney Laboratory, Soonchunhyang University, Seoul, Republic of Korea.
Sang Hun LeeMedical Science Research Institute, Soonchunhyang University Seoul Hospital, Seoul 04401, Republic of Korea; Department of Biochemistry, Soonchunhyang University, College of Medicine, Cheonan, 330-930, Republic of Korea. Electronic address: ykckss1114@nate.com.
Soonchunhyang University Hospital · KRSoonchunhyang University · KRUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although autologous human mesenchymal stem cells (hMSCs) are a promising source for regenerative stem cell therapy in chronic kidney disease (CKD), the barriers associated with pathophysiological conditions limit therapeutic applicability to patients. We confirmed that level of cellular prion protein (PrP

Indexed as

AnimalsBiomarkersCell ProliferationCytokinesDisease Models, AnimalHumansInflammation MediatorsIschemiaMembrane Potential, MitochondrialMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMiceMitochondriaMitophagyPrPC ProteinsRenal Insufficiency, ChronicBiomarkersCytokinesInflammation MediatorsPrPC ProteinsTaurochenodeoxycholic AcidursodoxicoltaurineCellular prion proteinChronic kidney diseaseMesenchymal stem cellMitochondriaMitophagyPINK1Tauroursodeoxycholic acid

Identifiers

PMID30785084
PMCPMC6383184
OpenAlexW2914889165

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.