Evidence map›Paper›PMID 30784724›Full record

ArticleJournal of affective disorders2019

Network dynamics of positive and negative affect in bipolar disorder.

Joshua Curtiss, Daniel Fulford, Stefan G Hofmann, Anda Gershon

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
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  16. A network structure of manic symptoms.Brain and behavior · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joshua CurtissDepartment of Psychological and Brain Sciences, Boston University, United States.
Daniel FulfordDepartment of Psychological and Brain Sciences, Boston University, United States; College of Health and Rehabilitation Sciences, Boston University, United States.
Stefan G HofmannDepartment of Psychological and Brain Sciences, Boston University, United States.
Anda GershonDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 USA. Electronic address: andagershon@gmail.com.
Boston University · USStanford University · US

Funding

Sleep and Circadian Dysregulation in Pediatric Bipolar DisorderK01MH100433 · NIMH · STANFORD UNIVERSITY · PI GERSHON, ANDA · 2014 to 2017
$723k
A mechanism of sleep disturbance in bipolar disorderF32MH076339 · NIMH · UNIVERSITY OF CALIFORNIA BERKELEY · PI GERSHON, ANDA · 2007 to 2009
$148k
NIMH NIH HHS F32 MH076339NIMH NIH HHS K01 MH100433
6 · The paper itself

Abstract

backgroundThe network approach to psychopathology has become increasingly popular. Little research has examined the dynamic network structure of mental disorders, and, to date, no study has investigated the network dynamics of positive affect, negative affect, and physical activity in bipolar disorder. This represents the first study to estimate the dynamic network structure of affect and physical activity in individuals with and without bipolar I disorder.

methodsAn intensive longitudinal design was used to assess positive affect, negative affect, and actigraphy-based estimates of physical activity. The overall sample consisted of 32 adults with bipolar I disorder and 36 healthy control participants. Eligible participants underwent an 8-week assessment period, in which once-per-day ratings of affect and actigraphy estimates were obtained. Participants were re-assessed on baseline measures afterwards. Dynamic network analysis was used to examine the network structure of affect and physical activity over time. Multilevel models were used to examine the relationship between autocorrelation and changes in depression symptoms among participants with bipolar disorder. LIMITATIONS: The network analyses assume stationarity. Future research should consider time-varying multilevel network models to better account for time trends.

resultsThe results of the temporal networks indicated that the directed edges between positive and negative affect were mostly positive among individuals with bipolar I disorder. Among healthy control participants, the directed edges between positive and negative affect were mostly negative in direction. Physical activity, as assessed by daily actigraphy indices, was more densely connected in the healthy control network than the bipolar disorder network. Furthermore, the results indicated that critical slowing down predicted worsening of mood symptoms in the bipolar I disorder group.

conclusionsThis study suggests that certain dynamic patterns of affect may be an underlying process that contributes to the maintenance of bipolar disorder. These results have both theoretical and practical implications.

Indexed as

AffectExerciseActigraphyAdultBipolar DisorderCase-Control StudiesHumansLongitudinal StudiesMiddle AgedModels, PsychologicalPsychopathologyYoung AdultActigraphyBipolar disorderNetwork analysisTime series

Identifiers

PMID30784724
PMCPMC7438157
OpenAlexW2912879773

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.