Evidence map›Paper›PMID 30784576›Full record

ArticleImmunity2019

The Secret Life of IgE-Producing Cells.

Carlos J Aranda, Maria A Curotto de Lafaille

Abstract readComment
In one paragraph

Article in Immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. DEPs Induce Local Ige Class Switching Independent of Their Ability to Stimulate iBALT de Novo Formation.International journal of environmental research and public health · 2022
    Article
  4. Article
  5. Review
  6. Article
  7. IgE producers in the gut expand the gut's role in food allergy.Nature reviews. Gastroenterology & hepatology · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Carlos J ArandaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA.
Maria A Curotto de LafailleDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, New York University School of Medicine, New York, NY 10016, USA; Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: maria.lafaille@med.nyu.edu.

Funding

Cellular and molecular mechanisms of IgE cell memory in allergic responsesR01AI130343 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CUROTTO DE LAFAILLE, MARIA A, LAFAILLE, JUAN · 2017 to 2021
$2.9M
The Origin and Memory of Human IgE ResponsesR21AI133076 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CUROTTO DE LAFAILLE, MARIA A · 2017 to 2018
$466k
NIAID NIH HHS R01 AI130343NIAID NIH HHS R21 AI133076
6 · The paper itself

Abstract

IgE antibodies are essential mediators of allergies. In a recent study in Science, Croote et al. (2018) characterize IgE cells isolated from individuals allergic to peanuts. Their findings provide insight into the differentiation of IgE cells in humans and have implications for our understanding of allergic disease.

Indexed as

AllergensHypersensitivityB-LymphocytesHumansImmunoglobulin ETranscriptomeAllergensImmunoglobulin E

Identifiers

PMID30784576
PMCPMC9832915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.