Evidence map›Paper›PMID 30784244›Full record

ArticleJournal of biomedical optics2019

Photoacoustic computed tomography of human extremities.

Parker Wray, Li Lin, Peng Hu, Lihong V Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 65 citations in OpenAlex.

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  20. Background-suppressed tumor-targeted photoacoustic imaging using bacterial carriers.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Parker WrayCalifornia Institute of Technology, Caltech Optical Imaging Laboratory, Department of Electrical Eng, United States.
Li LinCalifornia Institute of Technology, Caltech Optical Imaging Laboratory, Andrew and Peggy Cheng Depar, United States.
Peng HuWashington University in St. Louis, Department of Biomedical Engineering, St. Louis, Missouri, United States.
Lihong V WangCalifornia Institute of Technology, Caltech Optical Imaging Laboratory, Department of Electrical Eng, United States.
California Institute of Technology · USWashington University in St. Louis · US

Funding

PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
IN VIVO IMAGING OF SINGLE CIRCULATING CELLSR01CA186567 · NCI · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2013 to 2017
$3.6M
Safe, rapid & functional pediatric brain imaging using photoacoustic computed tomographyR01NS102213 · NINDS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ANASTASIO, MARK A, WANG, LIHONG · 2017 to 2021
$3.0M
NCI NIH HHS R01 CA186567NIBIB NIH HHS DP1 EB016986NINDS NIH HHS R01 NS102213
6 · The paper itself

Abstract

We present a method of imaging angiographic structures in human extremities, including hands, arms, legs, and feet, using a newly developed photoacoustic computed tomography (PACT) system. The system features deep penetration (1.8 cm in muscular tissues) with high spatial and temporal resolutions. A volumetric image is acquired within 5 to 15 s while each cross sectional image is acquired within 100  μs. Therefore, we see no blurring from motion in the imaging plane. Longitudinal and latitudinal cross-sectional images of a healthy volunteer clearly show the vascular network of each appendage and highlight the system's ability to image major and minor vasculatures, without the use of an external contrast or ionizing radiation. We also track heartbeat-induced arterial movement at a two-dimensional frame rate of 10 Hz. This work substantiates the idea that PACT could be used as a noninvasive method for imaging human vasculatures.

Indexed as

AngiographyArmArteriesArtifactsEquipment DesignFootHandHealthy VolunteersHeartHumansImage Processing, Computer-AssistedImaging, Three-DimensionalLegMotionPhantoms, ImagingPhotoacoustic Techniquesangiographyappendicular imagingdual-sided illuminationpanoramic photoacoustic detectionphotoacoustic computed tomography

Identifiers

PMID30784244
PMCPMC6380242
OpenAlexW2915205173

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.