ArticleJournal of diabetes investigation2019
Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults.
Article in Journal of diabetes investigation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- The mediating effect of blood pressure between healthy lifestyles and stroke: Results from the China Kadoorie Biobank study.Journal of biomedical research · 2025Article
- Diabetes in China: epidemiology, pathophysiology and multi-omics.Nature metabolism · 2025 · on this mapReview
- Interplay between oral health and lifestyle factors for cancer risk in rural and urban China: a population-based cohort study.Journal of the National Cancer Center · 2023Article
- Interplay between chronic widespread pain and lifestyle factors on the risk of type 2 diabetes: longitudinal data from the Norwegian HUNT Study.BMJ open diabetes research & care · 2023Article
- Association of healthy lifestyle with incident cardiovascular diseases among hypertensive and normotensive Chinese adults.Frontiers in cardiovascular medicine · 2023Article
- The multiple roles of life stress in metabolic disorders.Nature reviews. Endocrinology · 2023Review
- Stressful Life Events and Chronic Fatigue Among Chinese Government Employees: A Population-Based Cohort Study.Frontiers in public health · 2022Article
- The association between daily total physical activity and risk of cardiovascular disease among hypertensive patients: a 10-year prospective cohort study in China.BMC public health · 2021Article
- Associations between stressful life events and diabetes: Findings from the China Kadoorie Biobank study of 500,000 adults.Journal of diabetes investigation · 2019Article
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Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
AIMS/
introductionEvidence has shown that stressful life events are associated with the development of diabetes, yet studies in mainland China are scarce. In the present study, we explored the associations between cumulative and specific stressful life events and the prevalence of diabetes in Chinese adults. MATERIALS AND
methodsThe cross-sectional data were from the China Kadoorie Biobank study, which enrolled approximately 500,000 adults aged 30-79 years from 10 diverse regions of China. Logistic regression models were used to calculate the adjusted odds ratio (OR) and the 95% confidence interval (CI).
resultsOf the 473,607 participants, 25,301 (5.34%) had type 2 diabetes (2.68% clinically-identified and 2.66% screen-detected). Participants who experienced one and two or more stressful life events were 1.10-fold (OR 1.10, 95% CI 1.05-1.16) and 1.33-fold (OR 1.33, 95% CI 1.13-1.57) more likely to have type 2 diabetes. Three categories of work-related events (OR 1.15, 95% CI 1.01-1.31), as well as family-related events (OR 1.11, 95% CI 1.06-1.18) and personal-related events (OR 1.18, 95% CI 1.03-1.36), were associated with an increased likelihood of type 2 diabetes. Regarding the specific life events, the ORs of loss of job or retirement, as well as major conflict within family, death or major illness of other close family member and major injury or traffic accident, were 1.24 (95% CI 1.02-1.52), 1.24 (95% CI 1.08-1.43), 1.13 (95% CI 1.06-1.20) and 1.20 (95% CI 1.01-1.43), respectively.
conclusionsThe present study showed that cumulative and specific stressful life events were significantly associated with an increased prevalence of diabetes.
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