Evidence map›Paper›PMID 30784169›Full record

ArticleCancer science2019

A robust culture method for maintaining tumorigenic cancer stem cells in the hepatocellular carcinoma cell line Li-7.

Yukako Sato, Takeshi Yamada, Takashi Hiroyama, Kazuhiro Sudo, Naoyuki Hasegawa, Ichinosuke Hyodo, Yukio Nakamura

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yukako SatoDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID http://orcid.org/0000-0003-3491-310X
Takeshi YamadaDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Takashi HiroyamaCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan.
Kazuhiro SudoCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan.
Naoyuki HasegawaDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Ichinosuke HyodoDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yukio NakamuraCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan.
University of Tsukuba · JPRIKEN BioResource Research Center · JP

Funding

Ministry of Education, Culture, Sports, Science, and Technology of Japan 15K19312
6 · The paper itself

Abstract

Cancer tissues contain small populations of highly tumorigenic cells termed cancer stem cells (CSCs). Immortalized cell lines containing CSCs are valuable and powerful experimental tools for research into the characteristics of these stem cells. We previously reported that the hepatocellular carcinoma cell line Li-7 includes abundant CD13

Indexed as

Activated-Leukocyte Cell Adhesion MoleculeAnimalsAntigens, CDBiomarkers, TumorCarcinoma, HepatocellularCD13 AntigensCell Adhesion Molecules, NeuronalCell Culture TechniquesCell DifferentiationCell Line, TumorCell ProliferationCulture MediaFetal ProteinsGene Expression ProfilingHumansJagged-1 ProteinActivated-Leukocyte Cell Adhesion MoleculeALCAM protein, humanAntigens, CDBiomarkers, TumorCD13 AntigensCell Adhesion Molecules, NeuronalCulture MediaFetal ProteinsJAG1 protein, humanJagged-1 ProteinNOTCH1 protein, humanReceptor, Notch1Receptors, Fibroblast Growth FactorCD13CD166cell culturemTeSR1tumorigenicity

Identifiers

PMID30784169
PMCPMC6500967
OpenAlexW2916334881

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.