ArticleHuman brain mapping2019
Comorbidity of reading disabilities and ADHD: Structural and functional brain characteristics.
Article in Human brain mapping, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Examination of common and unique brain regions for atypical reading and math: a meta-analysis.Cerebral cortex (New York, N.Y. : 1991) · 2023Pooled it
- Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention.Neuroscience and biobehavioral reviews · 2022Pooled it
- Are there shared neural correlates between dyslexia and ADHD? A meta-analysis of voxel-based morphometry studies.Journal of neurodevelopmental disorders · 2019Pooled it
- Effects of fMRI neurofeedback of right inferior frontal cortex on inhibitory brain activation in children with ADHD.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Trial
- When Development Falls out of Sync: A Developmental Timing Framework for Learning Disabilities.Brain sciences · 2026Review
- Shared genetics between ADHD and reading/language abilities: Genome-wide correlations, stratified enrichment, cross-trait association, and mendelian randomization.JCPP advances · 2026Article
- A neuroanatomical basis for co-occurring low attention and low reading ability.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Reading Disabilities With and Without Co-Occurring ADHD: No Evidence for Additive Impact on Reading Skills.Scientific studies of reading : the official journal of the Society for the Scientific Study of Reading · 2026Article
- Dynamic modeling in neurocognitive frameworks of childhood ADHD: a review of inhibitory control and reward systems.Translational psychiatry · 2026Review
- Article
- *Co-Occurrence and Causality Among ADHD, Dyslexia, and Dyscalculia.Psychological science · 2025Article
- Examining the relationship between psychosocial adversity and inhibitory control: A functional magnetic resonance imaging study of children growing up in extreme poverty.Journal of experimental child psychology · 2025Article
- The underlying neuropsychological and neural correlates of the impaired Chinese reading skills in children with attention deficit hyperactivity disorder.European child & adolescent psychiatry · 2024Article
- Improving cognitive function in Chinese children with ADHD and/or RD through computerized working memory training.BMC psychology · 2024Article
- Comparison of Brain Function Between Medication-Naïve ADHD with and without Comorbidity in Chinese Children Using Resting-State fNIRS.Alpha psychiatry · 2024Article
- ADDing up?Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists · 2024Article
- Prevalence and trends of developmental disabilities among US children and adolescents aged 3 to 17 years, 2018-2021.Scientific reports · 2023Article
- Genetic architecture of ADHD and overlap with other psychiatric disorders and cognition-related phenotypes.Neuroscience and biobehavioral reviews · 2023Review
- Psycholinguistic profiling of children with sluggish cognitive tempo.Clinical linguistics & phonetics · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
Abstract
Reading disabilities (RD) and attention-deficit/hyperactivity disorder (ADHD) are two of the most common developmental disorders. RD and ADHD frequently co-occur, which raises questions about how the disorders interact and to what extent they can be differentiated. To date, the underlying neural mechanisms leading to RD-ADHD comorbidity (COM) are not understood. In this study, structural and functional magnetic resonance imaging (fMRI) were combined with comprehensive behavioral testing in order to characterize the behavior, brain structure, and neural correlates of executive function, phonological processing and reading fluency in 60 children with clinical diagnoses of RD, ADHD, or COM, and controls. Whole-brain analyses of variance were performed on cortical thickness values and on the data of the three fMRI tasks to investigate overall group differences. To validate these findings, a region of interest analysis was performed in regions that have previously been shown to exhibit group differences in children with RD or ADHD using the same paradigms. The neuroimaging results demonstrated structural and functional atypicalities for COM in regions that are frequently associated with deficits in children with isolated ADHD or RD. A combination of shared and distinctive brain alterations between the clinical groups was identified, supporting the multiple deficit model for ADHD, RD, and its comorbidity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.