Evidence map›Paper›PMID 30783886›Full record

ArticleJournal of robotic surgery2020

A prospective analysis of robotic targeted MRI-US fusion prostate biopsy using the centroid targeting approach.

Saiful Miah, Pol Servian, Amit Patel, Catherine Lovegrove, Lindsey Skelton, Taimur T Shah, David Eldred-Evans, Manit Arya, Henry Tam, Hashim U Ahmed and 1 more

Abstract read
In one paragraph

Article in Journal of robotic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. MUTUAL: Towards Holistic Sensing and Inference in the Operating Room.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2025
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  9. Article
  10. Article
  11. Article
  12. All change in the prostate cancer diagnostic pathway.Nature reviews. Clinical oncology · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saiful MiahDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK. saiful.miah@nhs.net.ORCID http://orcid.org/0000-0001-5777-518X
Pol ServianDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Amit PatelDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Catherine LovegroveDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Lindsey SkeltonDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Taimur T ShahDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
David Eldred-EvansDivision of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK.
Manit AryaDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Henry TamDepartment of Radiology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
Hashim U AhmedDivision of Surgery, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK.ORCID http://orcid.org/0000-0002-1611-4745
Mathias WinklerDepartment of Urology, Charing Cross Hospital, Imperial Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robotic prostate biopsy is an emerging technology. Recent development of this tool has allowed the performance of a transperineal prostate biopsy allowing pre-programmed standardized biopsy schemes. Prospective data collection was undertaken in 86 consecutive men who underwent robotically assisted transperineal prostate biopsy. All underwent a multi-parametric MRI pre-biopsy with centroid targeting followed by systematic template prostate biopsy. For the purposes of this study, our definition of clinically significant prostate cancer (csPCa) is any Gleason score > 6. Mean (SD) age, median (IQR) PSA, and median (IQR) prostate volume were 64.24 (6.97) years, of 7.79 ng/ml (6.5) and 45.06 cc (28), respectively. Overall, 44 (51.2%) men were diagnosed with csPCa. csPCa was detected in the targeted biopsies alone in 35 (40.1%) men. The addition of the 12-zone template biopsy increased the yield of csPCa for another 9 (10.5%) men. Of these 9 men, the majority (7) harbored primary pattern 3 disease and only 1 was identified to have high-grade disease. Out of these 9 men, 7 of them had the identification of csPCa in the sector, where a target was contained within that zone. Robotic-assisted prostate biopsy in our study has demonstrated a high detection of csPCa when combined with limited near-field sampling. Our study suggests the use of more accurate biopsy schemes such as ring-targeting of lesions to mitigate against systematic and random mathematical errors. Adoption of this tool and biopsy strategy would potentially avoid the increased morbidity associated with whole gland systematic unguided biopsies.

Indexed as

HumansImage-Guided BiopsyMagnetic Resonance ImagingMaleProspective StudiesProstateRobotic Surgical ProceduresUltrasonographyFusion biopsyRobotic prostate biopsyTargeted biopsy

Identifiers

PMID30783886
PMCPMC7000504

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.