Evidence map›Paper›PMID 30783876›Full record

ReviewQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019

Patterns, trends and methodological associations in the measurement and valuation of childhood health utilities.

Joseph Kwon, Sung Wook Kim, Wendy J Ungar, Kate Tsiplova, Jason Madan, Stavros Petrou

Abstract readReview
In one paragraph

Review in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Nothing about us, without us? A reflection on and call for involving children in the process of valuing child health.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  9. Review
  10. Article
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  12. A comparison of the Child Health Utility 9D and the Health Utilities Index for estimating health utilities in pediatric inflammatory bowel disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  13. Article
  14. Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
  15. Article
  16. EQ-5D-Y Value Set for Germany.PharmacoEconomics · 2022
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  19. Exploring EQ-5D-Y-3L Experience-Based VAS Values Derived Among Adolescents.Applied health economics and health policy · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joseph KwonSchool of Health and Related Research, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-2860-7280
Sung Wook KimWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Wendy J UngarProgram of Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada.
Kate TsiplovaProgram of Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada.
Jason MadanWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK.
Stavros PetrouWarwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Gibbet Hill Road, Coventry, CV4 7AL, UK. s.petrou@warwick.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo systematically assess patterns and temporal changes in the measurement and valuation of childhood health utilities and associations between methodological factors.

methodsStudies reporting childhood health utilities using direct or indirect valuation methods, published by June 2017, were identified through PubMed, Embase, Web of Science, PsycINFO, EconLit, CINAHL, Cochrane Library and PEDE. The following were explored: patterns in tariff application; linear trends in numbers of studies/samples and paediatric cost-utility analyses (CUAs) and associations between them; changes in proportions of studies/samples within characteristic-based categories over pre-specified periods; impact of National Institute for Health and Care Excellence (NICE) guidance on primary UK research and associations between valuation method, age and methodological factors.

results335 studies with 3974 samples covering all ICD-10 chapters, 23 valuation methods, 12 respondent types and 42 countries were identified by systematic review. 34.0% of samples using indirect methods compatible with childhood applied childhood-derived tariffs. There was no association between numbers of studies/samples and numbers of CUAs. Compared to 1990-2008, 2009-June 2017 saw a significant fall in the proportion of studies using case series; significant compositional changes across ICD-10 chapters and significantly higher sample proportions using childhood-specific and adult-specific indirect valuation methods, and based on pre-adolescents, self-assessment, self-administration and experienced health states. NICE guidance was weakly effective in promoting reference methods. Associations between valuation method, age and methodological factors were significant.

conclusion1990-2017 witnessed significant changes in primary research on childhood health utilities. Health technology assessment agencies should note the equivocal effect of methodological guidance on primary research.

Indexed as

Quality-Adjusted Life YearsChildCost-Benefit AnalysisHumansQuality of LifeResearch DesignSelf-AssessmentTechnology Assessment, BiomedicalChildhood health statesCost–utility analysisEconomic evaluationHealth utilityPRISMASystematic review

Identifiers

PMID30783876
PMCPMC6571090

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.