ArticleEnvironmental monitoring and assessment2019
Refined assessment of heavy metal-associated health risk due to the consumption of traditional animal medicines in humans.
Article in Environmental monitoring and assessment, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Article
- Investigation the Concentration Levels of Essential and Non-Essential Elements in Veterinary Vaccines by Inductively Coupled Plasma Mass Spectrometry.Biological trace element research · 2025Article
- Evaluation of Risk Factors Associated with Selected Elements in Veterinary Active Pharmaceutical Ingredients Using ICP-MS.Biological trace element research · 2025Article
- Analysis of Heavy Metal Characteristics and Health Risk Assessment of Dried Fish Marketed in Guangzhou, China.Biological trace element research · 2025Article
- Integrating ICP-MS and Chemometrics for Profiling Inorganic Elements in Lianhua Qingwen Capsules and Evaluating Health Risk.Biological trace element research · 2025Article
- Progress in quality control, detection techniques, speciation and risk assessment of heavy metals in marine traditional Chinese medicine.Chinese medicine · 2023Review
- Integrating Multi-Type Component Determination and Anti-Oxidant/-Inflammatory Assay to Evaluate the Impact of Pre-Molting Washing on the Quality and Bioactivity of Cicadae Periostracum.Molecules (Basel, Switzerland) · 2022Article
- Novel bioavailability-based risk assessment of Cd in earthworms and leeches utilizing in vitro digestion/Caco-2 and MDCK cells.Environmental science and pollution research international · 2022Article
- Medicinal Earthworm: Speciation and Bioaccessibility of Arsenic and Its Potential Health Risks.Frontiers in pharmacology · 2022Article
- Amassing of heavy metals in soils, vegetables and crop plants irrigated with wastewater: Health risk assessment of heavy metals in Dera Ghazi Khan, Punjab, Pakistan.Frontiers in plant science · 2022Article
- Uptake and Distribution Characteristic and Health Risk Assessment of Heavy Metal(loid)s in Platycodon Grandiflorum (Jacq.) A.DC. with Growth from a Medicinal Herb Garden of Xi'an, China.Biological trace element research · 2021Article
- Toxic element profile of ice cream in Bangladesh: a health risk assessment study.Environmental monitoring and assessment · 2021Article
- Bioaccumulation and risk assessment of heavy metals in soil-crop systems in Liujiang karst area, Southwestern China.Environmental science and pollution research international · 2021Article
- Heavy Metals and Probabilistic Risk Assessment viaFrontiers in pharmacology · 2021Article
- Innovative health risk assessments of heavy metals based on bioaccessibility due to the consumption of traditional animal medicines.Environmental science and pollution research international · 2020Article
- Fractionation analysis and health risk assessment of heavy metals in six traditional Chinese medicines.Environmental science and pollution research international · 2020Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Little is known about the extent of heavy metal accumulation in traditional Chinese medicines (TCMs). In this study, the levels of lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) in traditional animal medicines were monitored using inductively coupled plasma mass spectroscopy (ICP-MS). Additionally, for the first time, a heavy metal risk assessment strategy was used to evaluate the potential risks of traditional animal medicines by calculating estimated daily intake (EDI), target hazard quotient (THQ), and cancer risk (CR). To obtain a refined risk assessment, the frequency of exposure to traditional animal medicines was determined from questionnaire data, and the safe factor for TCM was applied. Based on the standard levels for leech, it was found that earthworm, hive, scorpion, and leech accumulated high levels of heavy metals. The combined THQ (cTHQ) values indicated that ingestion of most traditional animal medicines would not pose a risk to the health of either male or female human beings. However, it was indicated that attention should be paid to the potential risk associated with cicada slough, earthworm, scorpion, turtle shells, and hive. Among heavy metals, As and Hg contributed to a major extent to the risk to human health. The CR assessment for Pb and As indicated that, with the exception of earthworm, the cancer risk was less than the acceptable lifetime risk for both males and females. Owing to the higher body weight, both THQ and CR were generally lower for males than for females.
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