Evidence map›Paper›PMID 30783730›Full record

ArticleHNO2019

[Schirmer test for determining the moisture status of the nasal mucosa].

F Stupp, A Weigel, T K Hoffmann, F Sommer, A-S Grossi, J Lindemann

Abstract read
PubMed Publisher
In one paragraph

Article in HNO, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F StuppKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland. franziska.stupp@uniklinik-ulm.de.
A WeigelKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.
T K HoffmannKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.
F SommerKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.
A-S GrossiKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.
J LindemannKlinik für Hals‑, Nasen- und Ohrenheilkunde, Universitätsklinikum Ulm, Frauensteige 12, 89075, Ulm, Deutschland.
University Hospital Ulm · DEUniversitätsklinik für Hals-, Nasen- und Ohrenheilkunde · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is no established method to objectively measure the moisture status of nasal mucosa. In a pilot study it was shown that a nasal Schirmer test is a possible method. The aim of the current study was to check whether the nasal Schirmer test is suitable to define moisture status in cases with an expected pathological secretion. MATERIALS AND

methodsInitially, 154 subjects participated, of whom n = 112 were included (healthy n = 65, deviated septum n = 47, ♂ 60, ♀ 52, median age 33 years). After evaluation of various test strips, the most suitable one was placed on both sides of the mucosa of the anterior septum. Secretion running distance (SRD) was measured in mm after 10 min. In addition, rhinomanometry (AAR) and acoustic rhinometry (AR) were performed. Healthy volunteers and subjects with septum deviation were compared, and subjects were also compared in terms of smoking behavior and age (<60 and ≥60 years).

resultsThe total median SRD was 12 mm. SRDs between 9 and 14 mm were considered physiological. In non-smokers, SRD was significantly higher in all groups compared to smokers (p > 0.05). Nasal side, age, and deviated septum had no significant influence on SRD (p < 0.05). There were no correlations between SRD and AAR or AR.

conclusionOur results confirm that a statement about moisture of the nasal mucosa is possible based on a nasal Schirmer test. Standard values of SRD are relevantly influenced by the respective test strip. Smoking is associated with a drier mucosa. Further investigations on the nasal Schirmer test in patients with expected atrophy of the nose, e. g., Sjogren's or empty nose syndrome, should be performed.

Indexed as

Nasal MucosaNasal ObstructionAdultFemaleHumansMaleNasal SeptumNoseOtolaryngologyPilot ProjectsRhinomanometryRhinometry, AcousticAir conditioningHeatingHumidificationNasal dischargeRhinologic diagnostic

Identifiers

PMID30783730
OpenAlexW2915903178

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.