ArticleExperimental and therapeutic medicine2019
Inflammatory cytokines tumor necrosis factor-α, interleukin-8 and sleep monitoring in patients with obstructive sleep apnea syndrome.
Article in Experimental and therapeutic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Efficacy of curcumin in the management of oral submucous fibrosis: an umbrella review.Evidence-based dentistry · 2026Pooled it
- Genetic association between coffee/caffeine consumption and the risk of obstructive sleep apnea in the European population: a two-sample Mendelian randomization study.European journal of nutrition · 2023Pooled it
- Causal analysis between altered levels of interleukins and obstructive sleep apnea.Frontiers in immunology · 2022Pooled it
- Interleukin-8 concentrations in obstructive sleep apnea syndrome: a systematic review and meta-analysis.Bioengineered · 2021Pooled it
- Association between tumor necrosis factor alpha and obstructive sleep apnea in adults: a meta-analysis update.BMC pulmonary medicine · 2020Pooled it
- Role of endothelial dysfunction in sleep-disordered breathing in egyptian children with sickle cell disease.BMC pediatrics · 2024Article
- Unraveling the Complexities of Oxidative Stress and Inflammation Biomarkers in Obstructive Sleep Apnea Syndrome: A Comprehensive Review.Life (Basel, Switzerland) · 2024Review
- Association of Tumor Necrosis Factor-Alpha, Interleukin-1β, Interleukin-8, and Interferon-γ with Obstructive Sleep Apnea in Both Children and Adults: A Meta-Analysis of 102 Articles.Journal of clinical medicine · 2024Review
- Association of TNF-α (-308G/A) Gene Polymorphism with Changes in Circulating TNF-α Levels in Response to CPAP Treatment in Adults with Coronary Artery Disease and Obstructive Sleep Apnea.Journal of clinical medicine · 2023Article
- Upregulation of IL-8, osteonectin, and myonectin mRNAs by intermittent hypoxia via OCT1- and NRF2-mediated mechanisms in skeletal muscle cells.Journal of cellular and molecular medicine · 2022Article
- A Case-Control Study on the Changes in High-Sensitivity C-Reactive Protein and Tumor Necrosis Factor-Alpha Levels with Surgical Treatment of OSAS.International journal of molecular sciences · 2022Article
- Association between nocturnal hypoxemic burden and glucose metabolism.Sleep & breathing = Schlaf & Atmung · 2022Article
- Prevalence of sleep disturbance and the association between poor disease control in people with ankylosing spondylitis within the Australian clinical setting (ASLEEP study): a real-world observational study using the OPAL dataset.Clinical rheumatology · 2022Observational
- Systemic inflammation and sympathetic activation in gestational diabetes mellitus with obstructive sleep apnea.BMC pulmonary medicine · 2022Article
- Development and Comparison of Predictive Models Based on Different Types of Influencing Factors to Select the Best One for the Prediction of OSAHS Prevalence.Frontiers in psychiatry · 2022Article
- Serum Levels of TNF-α Are Increased in Patients with Rotator Cuff Tear and Sleep Disturbance.Diagnostics (Basel, Switzerland) · 2021Article
- Patients with obstructive sleep apnea have suppressed levels of soluble cytokine receptors involved in neurodegenerative disease, but normal levels with airways therapy.Sleep & breathing = Schlaf & Atmung · 2021Article
- Association ofJournal of clinical medicine · 2021Article
- TNF-α promotes insulin resistance in obstructive sleep apnea-hypopnea syndrome.Experimental and therapeutic medicine · 2021Article
- Influence of Obstructive Sleep Apnea on Systemic Inflammation in Pregnancy.Frontiers in medicine · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The present study investigated the changes of tumor necrosis factor-α (TNF-α), interleukin-8 (IL-8) and sleep ability in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). A total of 684 patients who were admitted to Xuzhou Central Hospital between June 2012 and June 2016 were enrolled to serve as the experimental group and 192 healthy subjects were selected as the control group. Polysomnography was performed on both groups, and serum TNF-α and IL-8 levels were measured by ELISA. Pearson's correlation analysis was used to analyze correlations between factors. Compared with control group, the levels of TNF-α and IL-8, the morning systolic and diastolic pressure in OSAHS group were significantly higher (P<0.01). Furthermore, the mean oxygen saturation (MSaO2) and lowest oxygen saturation (LSaO2) of the OSAHS group were significantly lower compared with those in control group (P<0.01). Results also indicated that TNF-α was positively correlated with apnea-hypopnea index (AHI), morning systolic and diastolic pressure (r=0.621, 0.464, 0.539; P<0.05), and negatively correlated with MSaO
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Registered trials
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