Evidence map›Paper›PMID 30783378›Full record

ArticleBioinformatics and biology insights2019

Combining Strengths for Multi-genome Visual Analytics Comparison.

Sergio Diaz-Del-Pino, Pablo Rodriguez-Brazzarola, Esteban Perez-Wohlfeil, Oswaldo Trelles

Abstract read
In one paragraph

Article in Bioinformatics and biology insights, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sergio Diaz-Del-PinoDepartment of Computer Architecture, University of Málaga and Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.ORCID https://orcid.org/0000-0002-9501-3300
Pablo Rodriguez-BrazzarolaDepartment of Computer Architecture, University of Málaga and Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.
Esteban Perez-WohlfeilDepartment of Computer Architecture, University of Málaga and Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.
Oswaldo TrellesDepartment of Computer Architecture, University of Málaga and Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eclosion of data acquisition technologies has shifted the bottleneck in molecular biology research from data acquisition to data analysis. Such is the case in Comparative Genomics, where sequence analysis has transitioned from genes to genomes of several orders of magnitude larger. This fact has revealed the need to adapt software to work with huge experiments efficiently and to incorporate new data-analysis strategies to manage results from such studies. In previous works, we presented GECKO, a software to compare large sequences; now we address the representation, browsing, data exploration, and post-processing of the massive amount of information derived from such comparisons. GECKO-MGV is a web-based application organized as client-server architecture. It is aimed at visual analysis of the results from both pairwise and multiple sequences comparison studies combining a set of common commands for image exploration with improved state-of-the-art solutions. In addition, GECKO-MGV integrates different visualization analysis tools while exploiting the concept of layers to display multiple genome comparison datasets. Moreover, the software is endowed with capabilities for contacting external-proprietary and third-party services for further data post-processing and also presents a method to display a timeline of large-scale evolutionary events. As proof-of-concept, we present 2 exercises using bacterial and mammalian genomes which depict the capabilities of GECKO-MGV to perform in-depth, customizable analyses on the fly using web technologies. The first exercise is mainly descriptive and is carried out over bacterial genomes, whereas the second one aims to show the ability to deal with large sequence comparisons. In this case, we display results from the comparison of the first

Indexed as

Bioinformaticsdata analysislayered image representationpairwise and multiple genome comparisonweb platform

Identifiers

PMID30783378
PMCPMC6365554

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.