Evidence map›Paper›PMID 30783361›Full record

ArticleAyu

Analgesic and anti-inflammatory activities of

Vrinda Govindan Nair, Pradeep Kumar Prajapati, K Nishteswar, Vidhya Unnikrishnan, Mukesh B Nariya

Abstract read
In one paragraph

Article in Ayu. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Ethnobotany, Phytochemistry, Biological Activities, and Health-Promoting Effects of the GenusEvidence-based complementary and alternative medicine : eCAM · 2022
    Review
  4. GC-MS Analysis and Various In Vitro and In Vivo Pharmacological Potential ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vrinda Govindan NairGeneral Physician, Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, VPSV Ayurveda College, Kottakkal, India.
Pradeep Kumar PrajapatiEx. Professor and HOD, Department of Rasashastra and Bhaishajya Kalpana Including Drug Research, VPSV Ayurveda College, Kottakkal, India.
K NishteswarEx. Professor and HOD, Department of Dravyaguna, VPSV Ayurveda College, Kottakkal, India.
Vidhya UnnikrishnanAsst. Professor, VPSV Ayurveda College, Kottakkal, India.
Mukesh B NariyaHead, Pharmacology Laboratory, IIPGT and RA, GAU, Jamnagar, Gujarat, India.
Vaidyaratnam P.S. Varier Ayurveda College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

aimThis study aims to evaluate analgesic and anti-inflammatory activities of MATERIALS AND

methodsShade-dried pseudobulb were pulverized into fine powder. The analgesic activity of test drug was evaluated with tail-flick response and formalin-induced paw licking and anti-inflammatory activity with carrageenan-induced paw edema and formaldehyde-induced edema in Charles Foster albino rats. Statistically, the values were assessed with one-way analysis of variance followed by Dunnett's multiple

resultsAdministration of pseudobulb powder showed significant increase in tail-flick response at 30 min (51.75%), at 60 min (108.24%), 120 min (81.12%), and 180 min (23.84%). Test drug produced nonsignificant inhibition of carrageenan-induced paw edema at 1 h (37.25%) and 5 h (15.67%) compared to control group and did not produced any effect in formalin-induced edema.

conclusionThe present study concluded that the test drug has central analgesic activity against radiant heat-induced pain, moderate anti-inflammatory activity against carrageenan-induced acute inflammation.

Indexed as

Analgesicanti-inflammatoryBulbophyllum neilgherrensecarrageenanpseudobulb

Identifiers

PMID30783361
PMCPMC6369610
OpenAlexW2912548448

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.