ArticleIndian journal of psychological medicine
Stressful Life Events and Relapse in Bipolar Affective Disorder: A Cross-Sectional Study from a Tertiary Care Center of Southern India.
Article in Indian journal of psychological medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Understanding Relapse in Bipolar Disorder at a Tertiary Mental Health Facility in Uganda.Neuropsychiatric disease and treatment · 2025Article
- Research on clinical aspects of bipolar disorder: A review of Indian studies.Indian journal of psychiatry · 2024Review
- Serious mental health conditions and exposure to adulthood trauma in low- and middle-income countries: a scoping review.Global mental health (Cambridge, England) · 2024Article
- COVID-19 and Severe Mental Illness: Impact on patients and its relation with their awareness about COVID-19.Psychiatry research · 2020Article
- Primary care physician's approach for mental health impact of COVID-19.Journal of family medicine and primary care · 2020Review
- The role of environmental stress and DNA methylation in the longitudinal course of bipolar disorder.International journal of bipolar disorders · 2020Article
- Role of TNF-α -308G/A Polymorphism in Bipolar Disorder and its Relationship with Clinical and Demographic Variables.Innovations in clinical neuroscienceArticle
- Comments on "Stressful Life Events and Relapse in Bipolar Affective Disorder".Indian journal of psychological medicineArticle
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3 authors.
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Abstract
backgroundBipolar affective disorder (BAD) is a severe mental illness which results in serious lifelong struggles and challenges. The full impact of stressful life events (SLEs) on the course of BAD is poorly understood. MATERIALS AND
methodsA cross-sectional study was conducted on 128 consecutive patients with BAD currently admitted with a relapse. Our objectives were (1) to estimate the proportion, type, and timing of preonset SLEs in relapsed BAD patients and (2) to study the association between SLEs and selected clinical variables in this group. Semi-structured proforma, Young Mania Rating Scale, Hamilton Rating Scale for Depression, Presumptive Stressful Life Events Scale, and Brief Psychiatric Rating Scale were used. Statistical analysis was done using R software for Windows.
resultsAbout 69.5% (89/128) of patients reported preonset SLEs - among which 50 (56.2%) had mania and 39 (43.8%) had depression. Conflict with in-laws and financial problems were the commonly reported SLEs. The mean duration between SLEs and the relapse was 19.73 ± 4.8 days. BPRS score was significantly high in subjects with preonset SLEs (
conclusionThis study emphasizes the significance of SLEs in the relapse and longitudinal course of BAD. Understanding the association of SLEs and relapse in BAD will help in predicting further relapses and developing newer pharmacological and nonpharmacological measures targeting this aspect, thereby maximizing both symptom reduction and quality of life in patients with BAD.
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