Evidence map›Paper›PMID 30783258›Full record

ArticleEye (London, England)2019

Differing presenting features of idiopathic intracranial hypertension in the UK and US.

R J Blanch, C Vasseneix, A Liczkowski, A Yiangou, A Aojula, J A Micieli, S P Mollan, N J Newman, V Biousse, B B Bruce and 1 more

Open access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Eye (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation of Racial, Ethnic, and Socioeconomic Disparities in Idiopathic Intracranial Hypertension.Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Observational
  8. Article
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  10. Review
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

R J BlanchDepartment of Ophthalmology, Emory University, Atlanta, GA, USA. blanchrj@bham.ac.uk.ORCID http://orcid.org/0000-0002-6142-3280
C VasseneixDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.
A LiczkowskiMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
A YiangouMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
A AojulaMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
J A MicieliDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.
S P MollanDepartment of Ophthalmology, University Hospital Birmingham NHS Trust, Birmingham, UK.ORCID http://orcid.org/0000-0002-6314-4437
N J NewmanDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.
V BiousseDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-3594-850X
B B BruceDepartment of Ophthalmology, Emory University, Atlanta, GA, USA.
A SinclairMetabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK. A.B.Sinclair@bham.ac.uk.ORCID http://orcid.org/0000-0003-2777-5132
Emory University · USUniversity of Birmingham · GBUniversity Hospitals Birmingham NHS Foundation Trust · GB

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
P30-Core Grant for Vision Research Core CP30EY006360 · NEI · EMORY UNIVERSITY · PI BOATRIGHT, JEFFREY H · 1986 to 2025
$15.3M
Department of Health NIHR-CS-011-028Medical Research Council MR/K015184/1NCRR NIH HHS UL1 RR025008NEI NIH HHS P30 EY006360
6 · The paper itself

Abstract

aimDemographic factors potentially influencing the presentation and severity of idiopathic intracranial hypertension (IIH) in the US vs. UK populations include obesity and ethnicity. We aimed to compare the presenting features of IIH between populations in the UK and US tertiary referral centres, to assess what population differences exist and whether these cause different presentations and impact on visual function.

methodsClinical data were collected on 243 consecutive UK IIH patients and 469 consecutive US IIH patients seen after 2012 in two tertiary centres. Visual function was defined as severe visual loss when Humphrey visual field mean deviation was <-15 dB, when Goldmann visual fields showed constriction or when visual acuity was <20/200.

resultsUS patients were more commonly of self-reported black race (58.9% vs. 7.1%) than UK patients, but had a similar mean body mass index (38.3 ± 0.63kg/m

conclusionsThe UK and the US cohorts had a similar average presenting BMI. However, the worse presenting visual function in the US IIH cohort was partially attributable to differences in the black populations in the two countries.

Indexed as

Visual AcuityAdolescentAdultBody Mass IndexCerebrospinal Fluid PressureFemaleHumansIncidenceMalePseudotumor CerebriUnited KingdomUnited StatesVision DisordersYoung Adult

Identifiers

PMID30783258
PMCPMC6662244
OpenAlexW2916502785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.