Evidence map›Paper›PMID 30783163›Full record

Observational studyScientific reports2019

Impact of gynecologic cancer on pelvic floor disorder symptoms and quality of life: an observational study.

Mathias Neron, Sophie Bastide, Renaud de Tayrac, Florent Masia, Catherine Ferrer, Majd Labaki, Laurent Boileau, Vincent Letouzey, Stephanie Huberlant

2 registry-linked trialsOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04515888 completednot on this mapstarted 2020, after this paper: background citation

Evaluation of the Prevalence of Pelvic Static Disorders in Women Treated for Localized Breast Cancer During Adjuvant Hormone Therapy.

TypeobservationalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2020 to 2021Enrolled246ConditionsBreast CancerArmsPFDI-20 / PFIQ-7 questionnaires
NCT06786091 nacompletednot on this mapstarted 2025, after this paper: background citation

Late Side-effects After Cervical Cancer Treatment - Prevention and Treatment

TypeinterventionalSponsorSt. Olavs HospitalRan2025 to 2026Enrolled25ConditionsPelvic Floor Disorder, Female Pelvic Floor Dysfunction, Female Sexual Dysfunction, Female Urinary IncontinenceArmsPelvic floor muscle training rehabilitation
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of treatment modality on pelvic floor dysfunction among uterine cancer survivors.International journal of gynecological cancer : official journal of the International Gynecological Cancer Society · 2022
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Bowel dysfunction in survivors of gynaecologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mathias NeronDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France. mathias.neron@orange.fr.
Sophie BastideDepartment of BESPIM (Biostatistics, Epidemiology, Public Health and Innovation in Methodology), Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Renaud de TayracDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Florent MasiaDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Catherine FerrerDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Majd LabakiDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Laurent BoileauDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Vincent LetouzeyDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Stephanie HuberlantDepartment of Obstetrics and Gynecology, Nîmes University Hospital, Univ., Montpellier, Nîmes, France.
Centre Hospitalier Universitaire de Nîmes · FRUniversité de Nîmes · FRInserm · FRNeuropsychiatrie : Recherche Epidemiologique et Clinique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of our observational prospective study was to investigate the severity and prevalence of urinary and pelvic floor disorders in gynecologic cancer survivors. All patients surviving gynecological cancer in the region as well as women receiving invitations to attend breast-screening checkups as the control population were asked to fill-in questionnaires assessing pelvic prolapse symptoms (PFDI-20, Wexner) and associated quality of life (PFIQ-7). Eighty-nine women were included in the cancer survivor group and 1088 in the control group. Pelvic floor symptoms (PFDI-20 questionnaire) were significantly worse in cancer survivors than in control women (score: 33.3 [14.6-74.1] vs. 20 [4.2-50.0], p = 0.0003). Urge incontinence was significantly worse in cancer survivors in both univariable (ORb = 2.061 [95% CI = 1.284-3.309], p = 0.0027) and multivariable analyses (ORa = 1.672 [95% CI = 1.014-2.758], p = 0.0442), as was fecal incontinence in univariable (ORb = 3.836 [95% CI = 1.710-8.602], p = 0.0011) and in multivariable (ORa = 3.862 [95% CI = 1.657-9.001], p = 0.0018) analyses. Women with benign hysterectomies had poorer quality of life and increased pelvic floor disorders compared to women with no history of surgery. Survivors of gynecological cancer experience significantly more pelvic floor symptoms and an associated reduction in quality of life.

Indexed as

Cancer SurvivorsPelvic Floor DisordersPelvic Organ ProlapseQuality of LifeSurveys and QuestionnairesAgedCross-Sectional StudiesFemaleGenital Neoplasms, FemaleHumansMiddle AgedProspective Studies

Identifiers

PMID30783163
PMCPMC6381087
OpenAlexW2917013291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.