ArticleInternational journal of oral science2019
Chronic inflammation deteriorates structure and function of collagen fibril in rat temporomandibular joint disc.
Article in International journal of oral science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Lysophosphatidic Acid (LPA) Salivary Species Detection and Whole-mount LPA Receptor Localization in Mouse Salivary Gland.bioRxiv : the preprint server for biology · 2026Article
- Bridging Temporomandibular Joint Structure, Function, and Pain: An Integrated Multiscale Perspective.Journal of dental research · 2026Review
- Hyperglycemia Induced in Sprague-Dawley Rats Modulates the Expression of CD36 and CD69 During Wound Healing.International journal of molecular sciences · 2025Article
- Piezoelectric nanofilms fabricated by coaxial electrospun polycaprolactone/Barium titanate promote Achilles tendon regeneration by reducing IL-17A/NF-κB-mediated inflammation.Bioactive materials · 2025Article
- Inflammation-related collagen fibril destruction contributes to temporomandibular joint disc displacement via NF-κB activation.International journal of oral science · 2025Article
- Temporomandibular disorders and mental health: shared etiologies and treatment approaches.The journal of headache and pain · 2025Review
- Quantitative Assessment of Temporomandibular Joint Space in Bruxers: A Cross-Sectional Radiographic Study.International journal of dentistry · 2025Article
- Endo 180 participates in collagen remodeling of the periodontal ligament during orthodontic tooth movement.BMC oral health · 2024Article
- Multi-class segmentation of temporomandibular joint using ensemble deep learning.Scientific reports · 2024Article
- Modulation of Stiffness-Dependent Macrophage Inflammatory Responses by Collagen Deposition.ACS biomaterials science & engineering · 2024Article
- A Comparative Study of Temporomandibular Joints in Adults with Definite Sleep Bruxism on Magnetic Resonance Imaging and Cone-Beam Computer Tomography Images.Journal of clinical medicine · 2023Article
- A systematic morphology study on the effect of high glucose on intervertebral disc endplate degeneration in mice.Heliyon · 2023Article
- The role of fibromodulin in inflammatory responses and diseases associated with inflammation.Frontiers in immunology · 2023Review
- Mechanotransduction in Skin Inflammation.Cells · 2022Review
- B6 Mouse Strain: The Best Fit for LPS-Induced Interstitial Cystitis Model.International journal of molecular sciences · 2021Article
- A noninvasive fluorescence imaging-based platform measures 3D anisotropic extracellular diffusion.Nature communications · 2021Article
- An Update on Mesenchymal Stem Cell-Centered Therapies in Temporomandibular Joint Osteoarthritis.Stem cells international · 2021Review
- Reactive Oxygen Species-Mediated Inflammation and Apoptosis in Hand-Foot Syndrome Induced by PEGylated Liposomal Doxorubicin.International journal of nanomedicine · 2021Article
- Collagen fibril abnormalities in human and mice abdominal aortic aneurysm.Acta biomaterialia · 2020Article
- Exploration of anti-inflammatory mechanism of forsythiaside A and forsythiaside B in CuSOJournal of neuroinflammation · 2020Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Collagen is the building component of temporomandibular joint (TMJ) discs and is often affected by inflammation in temporomandibular disorders. The macromechanical properties of collagen are deteriorated by chronic inflammation. However, the mechanism by which inflammation influences disc function remains unknown. The relationship between the ultrastructure and nanomechanical properties of collagen in inflamed discs should be clarified. Seven-week-old female Sprague-Dawley rats were randomly divided into two groups. Chronic TMJ inflammation was induced by intra-articular injection of complete Freund's adjuvant, and samples were harvested after 5 weeks. Picrosirius staining revealed multiple colours under polarized light, which represented alternative collagen bundles in inflamed discs. Using atomic force microscopy scanning, the magnitude of Young's modulus was reduced significantly accompanied with disordered collagen fibril arrangement with porous architecture of inflamed discs. Transmission electron microscopy scanning revealed a non-uniform distribution of collagen fibres, and oversized collagen fibrils were observed in inflamed discs. Fourier transform infrared microspectroscopy revealed a decrease in 1 338 cm
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.