ArticleProceedings of the National Academy of Sciences of the United States of America2019
Form and function of F-actin during biomineralization revealed from live experiments on foraminifera.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 64 citations in OpenAlex.
- A membrane-permeable small molecule biosensor accesses intractable cells and animals without genetic manipulation.bioRxiv : the preprint server for biology · 2026Article
- Statistical analysis of EBSD data confirms pronounced classical and non-classical pervasive crystallographic twinning in rotaliid foraminiferal calcite.Scientific reports · 2025Article
- Sponge Morphology of Osteosarcoma Finds Origin in Synergy Between Bone Synthesis and Tumor Growth.Nanomaterials (Basel, Switzerland) · 2025Article
- Bio-Informed Porous Mineral-Based Composites.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Proteomic characterization of a foraminiferal test's organic matrix.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Biocalcification in porcelaneous foraminifera.eLife · 2024Article
- ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis.eLife · 2024Article
- Mg-rich amorphous to Mg-low crystalline CaCOHeliyon · 2023Article
- Unique evolution of foraminiferal calcification to survive global changes.Science advances · 2023Article
- Taro raphide-associated proteins: Allergens and crystal growth.Plant direct · 2022Article
- Arrested in Glass: Actin within Sophisticated Architectures of Biosilica in Sponges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Test structure in some pioneer multichambered Paleozoic foraminifera.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Live Fluorescence Imaging of F-Actin Organization in Chick Whole Embryo Cultures Using SiR-Actin.Cells · 2021Article
- De novo transcriptome assembly for four species of crustose coralline algae and analysis of unique orthologous genes.Scientific reports · 2019Article
- Uncovering hidden structures: previously undescribed pseudopodia and ectoplasmic structures in planktonic foraminifera.Journal of plankton researchArticle
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Authors and funding
8 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the emergence of complex biomineralized forms has been investigated for over a century, still little is known on how single cells control morphology of skeletal structures, such as frustules, shells, spicules, or scales. We have run experiments on the shell formation in foraminifera, unicellular, mainly marine organisms that can build shells by successive additions of chambers. We used live imaging to discover that all stages of chamber/shell formation are controlled by dedicated actin-driven pseudopodial structures. Successive reorganization of an F-actin meshwork, associated with microtubular structures, is actively involved in formation of protective envelope, followed by dynamic scaffolding of chamber morphology. Then lamellar dynamic templates create a confined space and control mineralization separated from seawater. These observations exclude extracellular calcification assumed in selected foraminiferal clades, and instead suggest a semiintracellular biomineralization pattern known from other unicellular calcifying and silicifying organisms. These results give a challenging prospect to decipher the vital effect on geochemical proxies applied to paleoceanographic reconstructions. They have further implications for understanding multiscale complexity of biomineralization and show a prospect for material science applications.
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