Evidence map›Paper›PMID 30782756›Full record

Trial reportBMJ open2019

Depressive symptoms in people with vision impairment: a cross-sectional study to identify who is most at risk.

Claire Nollett, Barbara Ryan, Nathan Bray, Catey Bunce, Robin Casten, Rhiannon Tudor Edwards, David Gillespie, Daniel J Smith, Miles Stanford, Tom H Margrain

Abstract readMulticenter StudyPragmatic Clinical Trial
In one paragraph

Trial report in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
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  6. Personality traits and symptoms of anxiety and depression in patients with primary vitreous floaters.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
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  8. Feasibility and potential effectiveness of the IdentifEYE training programmes to address mental health problems in adults with vision impairment.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024
    Article
  9. Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Claire NollettCentre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0001-6676-4933
Barbara RyanSchool of Optometry and Vision Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0003-3722-8757
Nathan BrayCentre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK.
Catey BunceSchool of Population and Environmental Sciences, Kings College London, London, UK.ORCID 0000-0002-0935-3713
Robin CastenDepartment of Psychiatry and Human Behavior, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Rhiannon Tudor EdwardsCentre for Health Economics and Medicines Evaluation, Bangor University, Bangor, UK.
David GillespieCentre for Trials Research, College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK.
Daniel J SmithInstitute of Health and Wellbeing, University of Glasgow, Glasgow, UK.ORCID 0000-0002-2267-1951
Miles StanfordMedical Eye Unit, St Thomas' Hospital, London, UK.
Tom H MargrainSchool of Optometry and Vision Sciences, Cardiff University, Cardiff, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify the risk factors for significant depressive symptoms in people with visual impairment in England and Wales to provide information on who is most at risk and to whom support services could be targeted in future.

designA cross-sectional study using baseline data from a pragmatic randomised controlled trial. SETTING AND

participants990 participants aged 18 or over attending 1 of 14 low-vision rehabilitation primary care optometry-based clinics in South Wales or two hospital clinics in London. OUTCOME MEASURE: A score of ≥6 on the Geriatric Depression Scale-15 was classed as clinically significant depressive symptoms.

resultsIn a multivariable logistic regression model, significant depressive symptoms were associated with age (adjusted OR (AOR)=0.82, 95% CI: 0.66 to 0.90, p<0.001), ethnicity (AOR non-white compared with white=1.72, 95% CI: 1.05 to 2.81, p=0.031), total number of eye conditions (AOR for two vs one condition=0.98, 95% CI: 0.67 to 1.43; three or more vs one condition=0.34, 95% CI: 0.15 to 0.75, p=0.026), self-reported health (AOR for excellent vs poor=0.01, 95% CI: 0.00 to 0.12; very good vs poor=0.06, 95% CI: 0.03 to 0.13; good vs poor=0.14, 95% CI: 0.08 to 0.24; fair vs poor=0.28, 95% CI: 0.18 to 0.46, p<0.001) and self-reported visual functioning (AOR=1.45, 95% CI: 1.31 to 1.61, p<0.001).

conclusionYounger age, a non-white ethnicity, fewer eye conditions and poorer self-reported health and visual function are risk factors for significant depressive symptoms in this population. TRIAL REGISTRATION NUMBER: ISRCTN46824140; Pre-results.

Indexed as

AgedAged, 80 and overCross-Sectional StudiesDepressionEye DiseasesFemaleHumansLogistic ModelsMaleMiddle AgedPrimary Health CarePsychiatric Status Rating ScalesRisk FactorsROC CurveSelf ReportUnited Kingdomgeriatric medicineophthalmology

Identifiers

PMID30782756
PMCPMC6340416

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.