Observational studyBMJ open2019
HIV-related excess mortality and age-related comorbidities in patients with HIV aged ≥60: a relative survival analysis in the French Dat'AIDS cohort.
Observational study in BMJ open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02898987 (Dataids Prospective Observational Cohort on Quality of Care of French HIV Infected Patients), which is not on this map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dataids Prospective Observational Cohort on Quality of Care of French HIV Infected Patients
Who cites it
9 citing papers in PubMed.
- Development of a mortality risk prediction model for patients on antiretroviral therapy at Felege Hiwot Comprehensive Specialized Hospital: a retrospective cohort study.Scientific reports · 2026Article
- Excess Mortality in Persons with Concurrent HIV and Cancer Diagnoses: A Retrospective Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024Article
- Survival among people with HIV and their families in Denmark 1995-2021: a nationwide population-based cohort study.The Lancet regional health. Europe · 2024Article
- Profile of Newly Diagnosed Patients with HIV Infection in North-Eastern Romania.Medicina (Kaunas, Lithuania) · 2023Article
- Mortality in patients with acquired human immunodeficiency virus infection hospitalized in an intensive care unit during the period 2017-2019.Scientific reports · 2022Article
- The employment situation of people living with HIV: a closer look at the effects of the 2008 economic crisis.The European journal of health economics : HEPAC : health economics in prevention and care · 2022Article
- Epidemiological characteristics and adherence of a cohort of elderly people with HIV/AIDS in the Public Health System.Einstein (Sao Paulo, Brazil) · 2022Article
- Consensus statement on the assessment of comorbidities in people living with HIV in Romania.Germs · 2019Review
- Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe objective was to evaluate the association between age-related comorbidities (ARCs) and 5-year HIV-related excess mortality in people living with HIV aged ≥60 years.
designCohort study using relative survival analysis (Estève's model).
settingThe French multicentre prospective Dat'AIDS cohort that involves 12 French hospitals.
participantsInclusion of 1415 HIV-1 infected patients actively followed aged ≥60 years on January 2008, with a 5-year follow-up period in the late combination antiretroviral therapy era.
resultsAmong 1415 patients included, 154 died. By multivariable analysis, factors predictive of 5-year HIV-related excess mortality were non-AIDS-related cancer (adjusted excess HR (aEHR)=2.94; 95% CI 1.32 to 6.57), cardiovascular disease (aEHR=6.00; 95% CI 2.45 to 14.65), chronic renal disease (aEHR=4.86; 95% CI 2.24 to 10.53), cirrhosis (aEHR=3.58; 95% CI 1.25 to 10.28), hepatitis C co-infection (aEHR=3.63; 95% CI 1.44 to 9.12), body mass index<18.5 kg/m² (aEHR=4.10; 95% CI 1.61 to 10.48) and having a CD4 cell count ≤200/mm
conclusionsARCs, particularly cardiovascular disease and chronic renal disease, are predictive of HIV-related excess mortality, with an increase in hazard similar to that of CD4 cell count. TRIAL REGISTRATION NUMBER: NCT02898987.
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